⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10041943 | 1.00 | — | — | |
| SCHEMBL12810045 | 1.00 | — | — | |
| SCHEMBL10013538 | 1.00 | — | — | |
| SCHEMBL332747 | 1.00 | — | — | |
| SCHEMBL10231804 | 1.00 | — | — | |
| SCHEMBL7214312 | 1.00 | — | — | |
| SCHEMBL10013536 | 1.00 | — | — | |
| SCHEMBL3459775 | 1.00 | — | — | |
| SCHEMBL26823589 | 0.88 | LMNA (0.31) | — | |
| SCHEMBL13800901 | 0.86 | CA2 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6617315-B1 | Sugar-substituted benzimidazole derivatives are used for the treatment or prophylaxis of restenosis, particularly following angioplasty | CHAMBERLAIN STANLEY DAWES (US) | 2003-09-09 | — | — | US | disclosed |
| US-6204249-B1 | L-benzimidazole nucleosides | GLAXO WELLCOME INC. | 2001-03-20 | — | — | US | disclosed |