Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.35 |
| ▸ | IKBKB | O14920 | 3/20 | 0.35 |
| ▸ | CCR3 | P51677 | 5/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.34 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.34 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.34 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | CCNC | P24863 | 1/20 | 0.34 |
| ▸ | CDK8 | P49336 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3328179 | 1.00 | ALDH1A1 (0.39) | ALDH1A1HPGDPLA2G10IKBKBCCR3 | |
| SCHEMBL3325836 | 0.89 | IKBKB (0.38) | ALDH1A1HPGDIKBKBCCR3ABCC9 | |
| SCHEMBL3325841 | 0.89 | IKBKB (0.38) | ALDH1A1HPGDIKBKBCCR3ABCC9 | |
| SCHEMBL3329517 | 0.82 | GPER1 (0.41) | PLA2G10IKBKBPTPN1NPSR1MAPT | |
| SCHEMBL3329510 | 0.82 | GPER1 (0.41) | PLA2G10IKBKBPTPN1NPSR1MAPT | |
| SCHEMBL3603091 | 0.81 | PTPN1 (0.45) | ALDH1A1HPGDIKBKBCCR3PTPN1 | |
| SCHEMBL3326391 | 0.81 | ACLY (0.41) | ALDH1A1HPGDPLA2G10ABCC9ABCC8 | |
| SCHEMBL3599918 | 0.77 | MAPK14 (0.40) | ALDH1A1HPGDMAPTSMN1; SMN2ESR1 | |
| SCHEMBL3327323 | 0.76 | PTPN1 (0.36) | IKBKBPTPN1NPSR1MAPTKDM4E | |
| SCHEMBL3596170 | 0.76 | IKBKB (0.55) | ALDH1A1HPGDIKBKBCCR3PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100137388-A1 | Therapeutic Pro-Antibiotic Agents and Methods of Use Thereof | DENOVAMED INC. (CA) | 2010-06-03 | — | — | US | claimed |
| US-20100137388-A1 | Therapeutic Pro-Antibiotic Agents and Methods of Use Thereof | DENOVAMED INC. (CA) | 2010-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137388-A1 | Therapeutic Pro-Antibiotic Agents and Methods of Use Thereof | NAT1, NAPEPLD, NR1I2 | ALDH1A1 2098/4885HPGD 690/4885PLA2G10 3016/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.