Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 4/20 | 0.76 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.76 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.72 |
| ▸ | GAA | P10253 | 2/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.72 |
| ▸ | MAPT | P10636 | 1/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.72 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1574758 | 0.86 | PIK3CD (0.78) | PIK3CDPIK3CAPIK3CBALDH1A1GAA | |
| SCHEMBL3328268 | 0.86 | PIK3CD (1.00) | PIK3CDPIK3CAPIK3CBALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL6114749 | 0.85 | PIK3CD (0.76) | PIK3CDPIK3CAPIK3CBALDH1A1GAA | |
| SCHEMBL24829791 | 0.84 | ALDH1A1 (1.00) | PIK3CDPIK3CAPIK3CBALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL5010640 | 0.84 | PIK3CD (0.74) | PIK3CDPIK3CAPIK3CBALDH1A1GAA | |
| SCHEMBL17452585 | 0.82 | PIK3CD (0.72) | PIK3CDPIK3CAPIK3CBALDH1A1GAA | |
| SCHEMBL19902544 | 0.82 | PIK3CD (0.72) | PIK3CDPIK3CAPIK3CBALDH1A1GAA | |
| SCHEMBL6120595 | 0.81 | PIK3CD (0.70) | PIK3CDPIK3CAPIK3CBALDH1A1GAA | |
| SCHEMBL26346633 | 0.81 | ALDH1A1 (0.76) | PIK3CDPIK3CAPIK3CBALDH1A1GAA | |
| SCHEMBL625865 | 0.80 | PIK3CA (0.68) | PIK3CDPIK3CAPIK3CBALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100137312-A1 | NOVEL AROMATIC HETEROCYCLIC CARBOXYLIC ACID AMIDE DERIVATIVES USEFUL AS POTASSIUM CHANNEL MODULATORS | NEUROSEARCH A/S (DK) | 2010-06-03 | — | — | US | disclosed |
| EP-2148868-A1 | NOVEL AROMATIC HETEROCYCLIC CARBOXYLIC ACID AMIDE DERIVATIVES USEFUL AS POTASSIUM CHANNEL MODULATORS | NeuroSearch A/S (DK) | 2010-02-03 | — | — | EP | disclosed |
| WO-2008138917-A1 | NOVEL AROMATIC HETEROCYCLIC CARBOXYLIC ACID AMIDE DERIVATIVES USEFUL AS POTASSIUM CHANNEL MODULATORS | NEUROSEARCH A/S (DK) | 2008-11-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137312-A1 | NOVEL AROMATIC HETEROCYCLIC CARBOXYLIC ACID AMIDE DERIVATIVES USEFUL AS POTASSIUM CHANNEL MODULATORS | KCNH1, KCNJ2, KCNN2 | PIK3CD 1333/4885PIK3CA 1300/4885PIK3CB 1634/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.