Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.31 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.31 |
| ▸ | AHCY | P23526 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11977311 | 0.90 | GDA (0.33) | AHCY | |
| SCHEMBL497198 | 0.90 | KMT2A (0.36) | MEN1CSNK2A2RAB9ACSNK2BCSNK2A1 | |
| SCHEMBL8850 | 0.90 | GDA (0.33) | AHCY | |
| Isoguanine SCHEMBL887740 | 0.72 | PARP1 (0.36) | MEN1CSNK2A2RAB9ACSNK2BCSNK2A1 | |
| SCHEMBL533602 | 0.71 | MEN1 (0.39) | MEN1CSNK2A2RAB9ACSNK2BCSNK2A1 | |
| SCHEMBL2526551 | 0.71 | PARP1 (0.32) | MEN1CSNK2A2RAB9ACSNK2BCSNK2A1 | |
| 2,6-Diaminopurine SCHEMBL24052 | 0.71 | GDA (0.48) | — | |
| SCHEMBL3328527 | 0.71 | PDPK1 (0.54) | — | |
| 2,6-Diaminopurine SCHEMBL6423146 | 0.70 | GDA (0.47) | — | |
| 2,6-Diaminopurine SCHEMBL8757968 | 0.70 | GDA (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100137576-A1 | 5' O [(N ACYL)AMIDOPHOSPHATE] AND 5' O [(N ACYL)AMIDOTHIOPHOSPHATE] AND 5' O [(N ACYL)AMIDODITHIOPHOSPHATE] AND 5' O [(N ACYL)AMIDOSELENOPHOSPHATE] DERIVATIVES OF NUCLEOSIDES AND PROCESSES FOR THE MANUFACTURE THEREOF | CENTRUM BADAN MILEKULARNYCHI MAKROMOLEKULARNYCH, P (PL) | 2010-06-03 | — | — | US | claimed |
| EP-2097430-A1 | 5'-O-[(N-ACYL)AMIDOPHOSPHATE]- AND 5'-O-[(N-ACYL)AMIDOTHIOPHOSPHATE]- AND 5'-O-[(N-ACYL)AMIDODITHIOPHOSPHATE]- AND 5'-O-[N- ACYL)AMIDOSELENOPHOSPHATE-DERIVATIVES OF NUCLEOSIDES AND PROCESSES FOR THE MANUFACTURE THEREOF | Centrum Badan Molekularnych I Makromolekularnych Pan (PL) | 2009-09-09 | — | — | EP | claimed |
| WO-2008048128-A1 | 5'-O-[(N-ACYL)AMIDOPHOSPHATE]- AND 5'-O-[(N-ACYL)AMIDOTHIOPHOSPHATE]- AND 5'-O-[(N-ACYL)AMIDODITHIOPHOSPHATE]- AND 5'-O-[(N- ACYL)AMIDOSELENOPHOSPHATE]-DERIVATIVES OF NUCLEOSIDES AND PROCESSES FOR THE MANUFACTURE THEREOF | CENTRUM BADAN MOLEKULARNYCH I MAKROMOLEKULARNYCH, POLSKIEJ AKADEMII NAUK (PL) | 2008-04-24 | — | — | WO | claimed |