SCHEMBL332858

SCHEMBL332858

C=CCC[Si](CO)(CCC=C)CCC=C

nearest known ligand 0.37

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL236124 0.81 TSHR (0.39) TSHR
SCHEMBL234070 0.71 TSHR (0.45) TSHR
SCHEMBL235161 0.71 TSHR (0.45) TSHR
SCHEMBL8770117 0.71 TSHR (0.45) TSHR
SCHEMBL234882 0.69 TSHR (0.41) TSHR
SCHEMBL8064324 0.69 TSHR (0.41) TSHR
SCHEMBL4199442 0.69 TSHR (0.30) TSHR
SCHEMBL1781152 0.65
SCHEMBL11589496 0.63 TSHR (0.50) TSHR
SCHEMBL1836 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1913040-B1 POLYMER PARTICLES AND ENCAPSULATED COMPOSITIONS USING ORGANOBORANE AMINE COMPLEXES DOW SILICONES CORP (US) 2021-03-31 EP disclosed
EP-2321123-B1 METALLIZED PARTICLES FORMED FROM A DISPERSION DOW SILICONES CORP (US) 2018-08-08 EP disclosed
US-9080000-B2 Method of forming a non-random copolymer DOW CORNING CORPORATION (US) 2015-07-14 US disclosed
EP-2393855-B1 METHOD OF FORMING A NON-RANDOM COPOLYMER DOW CORNING (US) 2015-06-17 EP disclosed
US-8927062-B2 Method of preparing a substrate with a composition including an organoborane initiator DOW CORNING CORPORATION (US) 2015-01-06 US disclosed
EP-1926602-B1 AMBIENT LITHOGRAPHIC METHOD USING ORGANOBORANE AMINE COMPLEXES DOW CORNING (US) 2014-06-18 EP disclosed
US-8715828-B2 Emulsion of metallized particles comprising a compound having a pendant Si-H group DOW CORNING CORPORATION (US) 2014-05-06 US disclosed
US-8679585-B2 Ambient lithographic method using organoborane amine complexes DOW CORNING CORPORATION (US) 2014-03-25 US disclosed
US-8501887-B2 Radical polymerizable composition DOW CORNING CORPORATION (US) 2013-08-06 US disclosed
EP-2212457-B1 ARTICLE AND METHOD OF MANUFACTURING SAME DOW CORNING (US) 2013-07-24 EP disclosed
US-20080085983-A1 Polymer Particles And Encapsulated Compositions Using Organoborane Amine Complexes DOW SILICONES CORPORATION 2008-04-10 US disclosed
US-20080050552-A1 Organosilicon Functional Boron Amine Catalyst Complexes and Curable Compositions Made Therefrom DOW CORNING CORPORATION 2008-02-28 US disclosed
US-20070298223-A1 Curable compositions contain a free radical polymerizable organosilicon monomer, oligomer or polymer; an organoborane amine complex; and optionally an amine reactive compound; and a component capable of generating a gas when mixed with an active hydrogen compound and a catalyst; self-adherent elastomers DOW CORNING CORPORATION (US) 2007-12-27 US disclosed
US-20070246245-A1 Conductive Curable Compositions DOW SILICONES CORPORATION 2007-10-25 US disclosed
EP-1833864-A1 SILOXANES AND SILANES CURED BY ORGANOBORANE AMINE COMPLEXES Dow Corning Corporation (US) 2007-09-19 EP disclosed
EP-1805256-A1 CONDUCTIVE CURABLE COMPOSITIONS Dow Corning Corporation (US) 2007-07-11 EP disclosed
WO-2007040794-A1 AMBIENT LITHOGRAPHIC METHOD USING ORGANOBORANE AMINE COMPLEXES DOW CORNING CORPORATION (US) 2007-04-12 WO disclosed
WO-2006088571-A1 POLYMER PARTICLES AND ENCAPSULATED COMPOSITIONS USING ORGANOBORANE AMINE COMPLEXES DOW CORNING CORPORATION (US) 2006-08-24 WO disclosed
WO-2006073696-A1 SILOXANES AND SILANES CURED BY ORGANOBORANE AMINE COMPLEXES DOW CORNING CORPORATION (US) 2006-07-13 WO disclosed
WO-2006049792-A1 CONDUCTIVE CURABLE COMPOSITIONS DOW CORNING CORPORATION (US) 2006-05-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080050552-A1 Organosilicon Functional Boron Amine Catalyst Complexes and Curable Compositions Made Therefrom DBF4, MCM6, FANCF TSHR 4067/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.