SCHEMBL3328592

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL31257844	0.81	APP (0.50)	APPNPC1MTORRAB9AMAPT
	SCHEMBL2183993	0.80	APP (0.55)	APPNPC1MTORRAB9AMAPT
	SCHEMBL562815	0.80	APP (0.55)	APPNPC1MTORRAB9AMAPT
	SCHEMBL487465	0.76	MAPT (0.56)	APPNPC1MTORRAB9AMAPT
	Bicarbonate SCHEMBL28540490	0.76	MAPT (0.51)	APPNPC1MTORRAB9AMAPT
	SCHEMBL10723498	0.74	MAPT (0.50)	APPNPC1MTORRAB9AMAPT
	SCHEMBL18561130	0.73	MAPT (0.53)	APPMAPTKCNH2FFAR1
	SCHEMBL9906153	0.73	MAPT (0.53)	APPNPC1MTORRAB9AMAPT
	SCHEMBL10518285	0.73	APP (0.46)	APPNPC1MTORRAB9AMAPT
	SCHEMBL12935540	0.73	MAPT (0.53)	APPNPC1MTORRAB9AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.