Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lypressin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A known ✓ | P37288 | 8/20 | 0.87 |
| ▸ | AVPR2 known ✓ | P30518 | 6/20 | 0.87 |
| ▸ | AVPR1B known ✓ | P47901 | 6/20 | 0.87 |
| ▸ | OXTR | P30559 | 10/20 | 0.87 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.82 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.82 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.82 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lypressin SCHEMBL1650587 | 1.00 | OXTR (0.87) | OXTRAVPR1AAVPR2AVPR1BTBXA2R | |
| Lypressin SCHEMBL29471105 | 0.98 | OXTR (0.84) | OXTRAVPR1AAVPR2AVPR1BTBXA2R | |
| Ornipressin SCHEMBL1650220 | 0.98 | AVPR1A (0.88) | OXTRAVPR1AAVPR2AVPR1BTBXA2R | |
| Ornipressin SCHEMBL296322 | 0.98 | AVPR1A (0.88) | OXTRAVPR1AAVPR2AVPR1BTBXA2R | |
| SCHEMBL24239052 | 0.97 | OXTR (0.82) | OXTRAVPR1AAVPR2AVPR1BTBXA2R | |
| Felypressin SCHEMBL31138866 | 0.97 | AVPR1A (0.82) | OXTRAVPR1AAVPR2AVPR1BTBXA2R | |
| Felypressin SCHEMBL1650172 | 0.97 | AVPR1A (0.82) | OXTRAVPR1AAVPR2AVPR1BTBXA2R | |
| Felypressin SCHEMBL33291 | 0.97 | AVPR1A (0.82) | OXTRAVPR1AAVPR2AVPR1BTBXA2R | |
| Felypressin SCHEMBL361197 | 0.97 | AVPR1A (0.82) | OXTRAVPR1AAVPR2AVPR1BTBXA2R | |
| Ornipressin SCHEMBL4410141 | 0.97 | AVPR1A (0.85) | OXTRAVPR1AAVPR2AVPR1BTBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3489 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260124148-A1 | POLYPEPTIDE FORMULATIONS FOR ORAL DELIVERY | BHAMIS RES LABORATORY PVT LTD (IN) | 2026-05-07 | — | — | US | claimed |
| US-12533321-B2 | Polypeptide formulations for oral delivery | Bhami's Research Laboratory, Pvt. Ltd. (IN) | 2026-01-27 | — | — | US | claimed |
| EP-4633737-A1 | USES OF AVPR1A AGONISTS | Viage Therapeutics Inc. (US) | 2025-10-22 | — | — | EP | claimed |
| EP-4601623-A1 | POLYPEPTIDE FORMULATIONS FOR ORAL DELIVERY | Bhami's Research Laboratory, Pvt. Ltd. (IN) | 2025-08-20 | — | — | EP | claimed |
| US-20250241981-A1 | NOVEL COMPOSITION | ARECOR LIMITED (GB) | 2025-07-31 | — | — | US | claimed |
| WO-2024199558-A1 | METHOD OF PRODUCTION OF FIBERS AND A DEVICE FOR CARRYING OUT THE METHOD | CONTIPRO A.S. (CZ) | 2024-10-03 | — | — | WO | claimed |
| US-20240277624-A1 | NEW FORMULATIONS COMPRISING BIOLOGIC ACTIVE DRUGS | NANEXA AB (SE) | 2024-08-22 | — | — | US | claimed |
| EP-4413184-A1 | METHOD OF PREPARATION OF FIBRES AND DEVICE FOR CARRYING OUT THIS METHOD | Contipro a.s. (CZ) | 2024-08-14 | — | — | EP | claimed |
| WO-2024130011-A1 | USES OF AVPR1A AGONISTS | VIAGE THERAPEUTICS INC. (US) | 2024-06-20 | — | — | WO | claimed |
| US-20240122847-A1 | ORAL POLYPEPTIDE FORMULATIONS | Bhami's Research Laboratory, Pvt. Ltd. (IN) | 2024-04-18 | — | — | US | claimed |
| EP-0487520-A1 | COMPRESSED POWDER MEDICAMENTS. | ANESTA CORP (US) | 1992-06-03 | — | — | EP | claimed |
| WO-1991016929-A1 | A PHARMACEUTICAL PREPARATION CONTAINING N-GLYCOFUROLS AND N-ETHYLENE GLYCOLS | NOVO NORDISK A/S (DK) | 1991-11-14 | — | — | WO | claimed |
| US-5023088-A | Drug delivery dispenser | ALZA CORPORATION (US) | 1991-06-11 | — | — | US | claimed |
| WO-1991003099-A1 | COMPRESSED POWDER MEDICAMENTS | ANESTA CORPORATION (US) | 1991-03-07 | — | — | WO | claimed |
| US-4957494-A | Multi-layer delivery system | ALZA CORPORATION (US) | 1990-09-18 | — | — | US | claimed |
| US-4878892-A | BATTERY POWERED | DRUG DELIVERY SYSTEMS INC. (US) | 1989-11-07 | — | — | US | claimed |
| EP-0278474-A1 | Electrolytic transdermal delivery of polypeptides | Drug Delivery Systems Inc. (US) | 1988-08-17 | — | — | EP | claimed |
| US-4622244-A | SOLIDIFICATION | THE WASHINGTON UNIVERSITY (US) | 1986-11-11 | — | — | US | claimed |
| US-4427762-A | DEVELOPMENT WITH ALKALINE DEVELOPER MIXTURE | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1984-01-24 | — | — | US | claimed |
| EP-0082015-A1 | Method of forming an image with a photographic cuprous halide material | KONICA CORPORATION (JP) | 1983-06-22 | — | — | EP | claimed |