Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 10/20 | 0.88 |
| ▸ | AVPR1B | P47901 | 8/20 | 0.88 |
| ▸ | AVPR2 | P30518 | 7/20 | 0.88 |
| ▸ | OXTR | P30559 | 7/20 | 0.88 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.79 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.79 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.79 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ornipressin SCHEMBL296322 | 1.00 | AVPR1A (0.88) | AVPR1AAVPR1BAVPR2OXTRTBXA2R | |
| Ornipressin SCHEMBL4410141 | 0.98 | AVPR1A (0.85) | AVPR1AAVPR1BAVPR2OXTRTBXA2R | |
| Lypressin SCHEMBL33287 | 0.98 | OXTR (0.87) | AVPR1AAVPR1BAVPR2OXTRTBXA2R | |
| Lypressin SCHEMBL1650587 | 0.98 | OXTR (0.87) | AVPR1AAVPR1BAVPR2OXTRTBXA2R | |
| Ornipressin SCHEMBL5200435 | 0.97 | AVPR1A (0.83) | AVPR1AAVPR1BAVPR2OXTRTBXA2R | |
| Lypressin SCHEMBL29471105 | 0.97 | OXTR (0.84) | AVPR1AAVPR1BAVPR2OXTRTBXA2R | |
| SCHEMBL24239052 | 0.96 | OXTR (0.82) | AVPR1AAVPR1BAVPR2OXTRTBXA2R | |
| Felypressin SCHEMBL1650172 | 0.95 | AVPR1A (0.82) | AVPR1AAVPR1BAVPR2OXTRTBXA2R | |
| Felypressin SCHEMBL31138866 | 0.95 | AVPR1A (0.82) | AVPR1AAVPR1BAVPR2OXTRTBXA2R | |
| Felypressin SCHEMBL361197 | 0.95 | AVPR1A (0.82) | AVPR1AAVPR1BAVPR2OXTRTBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7927613-B2 | Pharmaceutical co-crystal compositions | UNIVERSITY OF SOUTH FLORIDA (US) | 2011-04-19 | — | — | US | disclosed |
| US-7790905-B2 | Pharmaceutical propylene glycol solvate compositions | MCNEIL-PPC, INC. (US) | 2010-09-07 | — | — | US | disclosed |