Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 10/20 | 0.43 |
| ▸ | HTR2C | P28335 | 3/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3329473 | 1.00 | HTR2B (0.43) | HTR2BHTR2CTHRBRAB9AMEN1 | |
| SCHEMBL13318725 | 0.78 | HTR2B (0.48) | HTR2BHTR2CTHRBRAB9AKMT2A | |
| Ebaresdax SCHEMBL22288068 | 0.73 | PIM1 (0.38) | RAB9AMEN1KMT2AALDH1A1HPGD | |
| Ebaresdax SCHEMBL22285901 | 0.73 | PIM1 (0.38) | RAB9AMEN1KMT2AALDH1A1HPGD | |
| Ebaresdax SCHEMBL11927657 | 0.73 | PIM1 (0.38) | RAB9AMEN1KMT2AALDH1A1HPGD | |
| Ebaresdax SCHEMBL11927658 | 0.73 | PIM1 (0.38) | RAB9AMEN1KMT2AALDH1A1HPGD | |
| Ebaresdax SCHEMBL22285896 | 0.72 | PIM1 (0.37) | RAB9AMEN1KMT2AALDH1A1HPGD | |
| Ebaresdax SCHEMBL22285897 | 0.72 | PIM1 (0.37) | RAB9AMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL5498678 | 0.72 | BCL2L1 (0.40) | RAB9AALDH1A1HPGDBCL2L1KDM4E | |
| SCHEMBL3305343 | 0.69 | HTR2B (0.51) | HTR2BHTR2CRAB9AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100137346-A1 | DESFERRITHIOCIN ANALOGUE ACTINIDE DECORPORATION AGENTS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2010-06-03 | — | — | US | disclosed |
| EP-2101764-A2 | DESFERRITHIOCIN ANALOGUE ACTINIDE DECORPORATION AGENTS | UNIVERSITY OF FLORIDA (US) | 2009-09-23 | — | — | EP | disclosed |
| WO-2008130395-A2 | DESFERRITHIOCIN ANALOGUE ACTINIDE DECORPORATION AGENTS | UNIVERSITY OF FLORIDA (US) | 2008-10-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137346-A1 | DESFERRITHIOCIN ANALOGUE ACTINIDE DECORPORATION AGENTS | TFRC, SLC40A1, FIBP | HTR2B 3077/4885HTR2C 3801/4885THRB 978/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.