Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 5/20 | 0.47 |
| ▸ | WNT3A | P56704 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19492343 | 0.86 | MAPT (0.42) | CTNNB1WNT3AALDH1A1GAAMAPT | |
| SCHEMBL13840329 | 0.85 | CTNNB1 (0.37) | CTNNB1WNT3AALDH1A1GAAMAPT | |
| SCHEMBL3356952 | 0.80 | MAPT (0.39) | ALDH1A1GAAMAPTHSD17B10EPHX2 | |
| SCHEMBL20741917 | 0.77 | LMNA (0.48) | CTNNB1WNT3AGAAMAPTNPC1 | |
| SCHEMBL20786544 | 0.77 | MAPT (0.47) | CTNNB1WNT3AALDH1A1GAAMAPT | |
| SCHEMBL5878708 | 0.77 | CTNNB1 (0.50) | CTNNB1WNT3AALDH1A1MAPTNPC1 | |
| SCHEMBL13075986 | 0.77 | CTNNB1 (0.47) | CTNNB1WNT3AALDH1A1MAPTNPC1 | |
| SCHEMBL13035785 | 0.77 | CTNNB1 (0.43) | CTNNB1WNT3AMAPTLMNASLC5A2 | |
| SCHEMBL15627021 | 0.77 | CTNNB1 (0.46) | CTNNB1WNT3AMAPTNPC1RAB9A | |
| SCHEMBL18352140 | 0.77 | KDM4E (0.47) | CTNNB1WNT3AALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11311528-B2 | Oxo-tetrahydro-isoquinoline carboxylic acids as STING inhibitors | MERCK SHARP & DOHME CORP. (US) | 2022-04-26 | — | — | US | disclosed |
| EP-3473621-B1 | METHOD FOR PRODUCING DIPHENYLMETHANE DERIVATIVE | DAE WOONG PHARMA (KR) | 2021-08-04 | — | — | EP | disclosed |
| US-20210052573-A1 | OXO-TETRAHYDRO-ISOQUINOLINE CARBOXYLIC ACIDS AS STING INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2021-02-25 | — | — | US | disclosed |
| EP-3663292-A1 | DIPHENYLMETHANE DERIVATIVE IN CRYSTALLINE FORM | Daewoong Pharmaceutical Co., Ltd. (KR) | 2020-06-10 | — | — | EP | disclosed |
| EP-3473621-A1 | METHOD FOR PRODUCING DIPHENYLMETHANE DERIVATIVE | Daewoong Pharmaceutical Co., Ltd. (KR) | 2019-04-24 | — | — | EP | disclosed |
| US-20190047968-A1 | 6-ACYL-1,2,4-TRIAZINE-3,5-DIONE DERIVATIVE AND HERBICIDES | FMC CORP (US) | 2019-02-14 | — | — | US | disclosed |
| EP-2714032-B1 | NOVEL DIPHENYLMETHANE DERIVATIVES AS SGLT2 INHIBITORS | GREEN CROSS CORP (KR) | 2019-01-16 | — | — | EP | disclosed |
| WO-2017217792-A1 | METHOD FOR PRODUCING DIPHENYLMETHANE DERIVATIVE | 주식회사 대웅제약 | 2017-12-21 | — | — | WO | disclosed |
| US-20170129861-A1 | 6-ACYL-1,2,4-TRIAZINE-3,5-DIONE DERIVATIVE AND HERBICIDES | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2017-05-11 | — | — | US | disclosed |
| US-20170129861-A1 | 6-ACYL-1,2,4-TRIAZINE-3,5-DIONE DERIVATIVE AND HERBICIDES | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2017-05-11 | — | — | US | disclosed |
| US-20140213642-A1 | NOVEL C-ARYL ANSA SGLT2 INHIBITORS | GREEN CROSS CORPORATION (KR) | 2014-07-31 | — | — | US | disclosed |
| US-20140088079-A1 | NOVEL DIPHENYLMETHANE DERIVATIVES AS SGLT2 INHIBITORS | GREEN CROSS CORPORATION (KR) | 2014-03-27 | — | — | US | disclosed |
| EP-2493880-B1 | HETEROBICYCLE-SUBSTITUTED AZOLYL BENZENE FUNGICIDES | DU PONT (US) | 2013-09-18 | — | — | EP | disclosed |
| US-20130102468-A1 | 6-ACYL-1,2,4-TRIAZINE-3,5-DIONE DERIVATIVE AND HERBICIDES | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2013-04-25 | — | — | US | disclosed |
| US-20130102468-A1 | 6-ACYL-1,2,4-TRIAZINE-3,5-DIONE DERIVATIVE AND HERBICIDES | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2013-04-25 | — | — | US | disclosed |
| WO-2012165914-A2 | NOVEL DIPHENYLMETHANE DERIVATIVES AS SGLT2 INHIBITORS | GREEN CROSS CORPORATION (KR) | 2012-12-06 | — | — | WO | disclosed |
| US-20120202815-A1 | HETEROBICYCLE-SUBSTITUTED AZOLYL BENZENE FUNGICIDES | E.I.DU PONT DE NEMOURS AND COMPANY (US) | 2012-08-09 | — | — | US | disclosed |
| US-20120202815-A1 | HETEROBICYCLE-SUBSTITUTED AZOLYL BENZENE FUNGICIDES | E.I.DU PONT DE NEMOURS AND COMPANY (US) | 2012-08-09 | — | — | US | disclosed |
| WO-2012002096-A1 | 6-ACYL-1,2,4-TRIAZINE-3,5-DIONE DERIVATIVE AND HERBICIDES | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2012-01-05 | — | — | WO | disclosed |
| WO-2011059619-A1 | HETEROBICYCLE-SUBSTITUTED AZOLYL BENZENE FUNGICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-05-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120202815-A1 | HETEROBICYCLE-SUBSTITUTED AZOLYL BENZENE FUNGICIDES | CBR3, CBR1, CYP2S1 | CTNNB1 3818/4885WNT3A 4337/4885ALDH1A1 3110/4885 |
| US-11311528-B2 | Oxo-tetrahydro-isoquinoline carboxylic acids as STING inhibitors | STING1, MAVS, CGAS | CTNNB1 4359/4885WNT3A 4573/4885ALDH1A1 4060/4885 |
| US-20140088079-A1 | NOVEL DIPHENYLMETHANE DERIVATIVES AS SGLT2 INHIBITORS | SLC5A2, SLC5A1, SLC2A8 | CTNNB1 1259/4885WNT3A 2902/4885ALDH1A1 1061/4885 |
| US-20170129861-A1 | 6-ACYL-1,2,4-TRIAZINE-3,5-DIONE DERIVATIVE AND HERBICIDES | DDT, AADAC, DAZAP1 | CTNNB1 4438/4885WNT3A 2248/4885ALDH1A1 144/4885 |
| US-20140213642-A1 | NOVEL C-ARYL ANSA SGLT2 INHIBITORS | SLC5A2, SLC5A1, SLC2A1 | CTNNB1 2487/4885WNT3A 3157/4885ALDH1A1 550/4885 |
| US-20130102468-A1 | 6-ACYL-1,2,4-TRIAZINE-3,5-DIONE DERIVATIVE AND HERBICIDES | CBR3, DDT, CBR1 | CTNNB1 3393/4885WNT3A 1197/4885ALDH1A1 272/4885 |
| US-20190047968-A1 | 6-ACYL-1,2,4-TRIAZINE-3,5-DIONE DERIVATIVE AND HERBICIDES | DDT, AADAC, DAZAP1 | CTNNB1 4438/4885WNT3A 2248/4885ALDH1A1 144/4885 |
| US-20210052573-A1 | OXO-TETRAHYDRO-ISOQUINOLINE CARBOXYLIC ACIDS AS STING INHIBITORS | STING1, MAVS, CGAS | CTNNB1 4359/4885WNT3A 4573/4885ALDH1A1 4060/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.