Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | MMP12 | P39900 | 1/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.33 |
| ▸ | TUBB | P07437 | 2/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.33 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.33 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.33 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.33 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.33 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.33 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.33 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.33 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.33 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11380998 | 0.83 | CYP2A6 (0.37) | MAPTALDH1A1GAAHSD17B10EPHX2 | |
| SCHEMBL3329915 | 0.80 | CTNNB1 (0.47) | MAPTALDH1A1GAAHSD17B10EPHX2 | |
| SCHEMBL5545052 | 0.75 | TUBB4A (0.33) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL16042250 | 0.75 | AHR (0.46) | MAPTCYP1A2TDP1CA2CYP19A1 | |
| SCHEMBL23844440 | 0.75 | LMNA (0.34) | MAPTALDH1A1GAATUBB4ATUBB | |
| SCHEMBL15911961 | 0.75 | PARP1 (0.41) | MAPTALDH1A1CYP2A6CYP1A2TUBB4A | |
| SCHEMBL8930712 | 0.74 | TUBB4A (0.35) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL6068629 | 0.73 | CYP19A1 (0.35) | MAPTALDH1A1GAAHSD17B10EPHX2 | |
| SCHEMBL13840329 | 0.71 | CTNNB1 (0.37) | MAPTALDH1A1GAAHSD17B10NPC1 | |
| SCHEMBL22914429 | 0.71 | SLC5A2 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3473621-A1 | METHOD FOR PRODUCING DIPHENYLMETHANE DERIVATIVE | Daewoong Pharmaceutical Co., Ltd. (KR) | 2019-04-24 | — | — | EP | disclosed |
| US-10221144-B2 | Antibacterial compounds having broad spectrum of activity | AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. (IT) | 2019-03-05 | — | — | US | disclosed |
| US-20190047968-A1 | 6-ACYL-1,2,4-TRIAZINE-3,5-DIONE DERIVATIVE AND HERBICIDES | FMC CORP (US) | 2019-02-14 | — | — | US | disclosed |
| EP-2714032-B1 | NOVEL DIPHENYLMETHANE DERIVATIVES AS SGLT2 INHIBITORS | GREEN CROSS CORP (KR) | 2019-01-16 | — | — | EP | disclosed |
| US-20170369450-A1 | ANTIBACTERIAL COMPOUNDS HAVING BROAD SPECTRUM OF ACTIVITY | AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. (IT) | 2017-12-28 | — | — | US | disclosed |
| WO-2017217792-A1 | METHOD FOR PRODUCING DIPHENYLMETHANE DERIVATIVE | 주식회사 대웅제약 | 2017-12-21 | — | — | WO | disclosed |
| EP-2709985-B1 | AMINE DERIVATIVES AS POTASSIUM CHANNEL BLOCKERS | BIONOMICS LTD (AU) | 2017-10-04 | — | — | EP | disclosed |
| US-20170129861-A1 | 6-ACYL-1,2,4-TRIAZINE-3,5-DIONE DERIVATIVE AND HERBICIDES | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2017-05-11 | — | — | US | disclosed |
| US-20170129861-A1 | 6-ACYL-1,2,4-TRIAZINE-3,5-DIONE DERIVATIVE AND HERBICIDES | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2017-05-11 | — | — | US | disclosed |
| US-9573909-B2 | 6-acyl-1,2,4-triazine-3,5-dione derivative and herbicides | FMC CORPORATION (US) | 2017-02-21 | — | — | US | disclosed |
| WO-2012165914-A2 | NOVEL DIPHENYLMETHANE DERIVATIVES AS SGLT2 INHIBITORS | GREEN CROSS CORPORATION (KR) | 2012-12-06 | — | — | WO | disclosed |
| US-8318981-B2 | Imidate compound and use thereof for pest control | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-11-27 | — | — | US | disclosed |
| US-8318981-B2 | Imidate compound and use thereof for pest control | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-11-27 | — | — | US | disclosed |
| US-20120202815-A1 | HETEROBICYCLE-SUBSTITUTED AZOLYL BENZENE FUNGICIDES | E.I.DU PONT DE NEMOURS AND COMPANY (US) | 2012-08-09 | — | — | US | disclosed |
| US-20120202815-A1 | HETEROBICYCLE-SUBSTITUTED AZOLYL BENZENE FUNGICIDES | E.I.DU PONT DE NEMOURS AND COMPANY (US) | 2012-08-09 | — | — | US | disclosed |
| WO-2012002096-A1 | 6-ACYL-1,2,4-TRIAZINE-3,5-DIONE DERIVATIVE AND HERBICIDES | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2012-01-05 | — | — | WO | disclosed |
| WO-2011059619-A1 | HETEROBICYCLE-SUBSTITUTED AZOLYL BENZENE FUNGICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-05-19 | — | — | WO | disclosed |
| US-20100210683-A1 | IMIDATE COMPOUND AND USE THEREOF FOR PEST CONTROL | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2010-08-19 | — | — | US | disclosed |
| US-20100210683-A1 | IMIDATE COMPOUND AND USE THEREOF FOR PEST CONTROL | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2010-08-19 | — | — | US | disclosed |
| US-4260610-A | Disubstituted piperazines | SCIENCE UNION ET CIE (FR) | 1981-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120202815-A1 | HETEROBICYCLE-SUBSTITUTED AZOLYL BENZENE FUNGICIDES | CBR3, CBR1, CYP2S1 | MAPT 4549/4885ALDH1A1 3110/4885GAA 4112/4885 |
| US-20170129861-A1 | 6-ACYL-1,2,4-TRIAZINE-3,5-DIONE DERIVATIVE AND HERBICIDES | DDT, AADAC, DAZAP1 | MAPT 3711/4885ALDH1A1 144/4885GAA 657/4885 |
| US-20100210683-A1 | IMIDATE COMPOUND AND USE THEREOF FOR PEST CONTROL | CYP1A1, CYC1, C1S | MAPT 4511/4885ALDH1A1 398/4885GAA 3852/4885 |
| US-20170369450-A1 | ANTIBACTERIAL COMPOUNDS HAVING BROAD SPECTRUM OF ACTIVITY | MRPL21, ABCG2, CLPP | MAPT 3361/4885ALDH1A1 3437/4885GAA 377/4885 |
| US-10221144-B2 | Antibacterial compounds having broad spectrum of activity | MRPL21, ABCG2, CLPP | MAPT 3361/4885ALDH1A1 3437/4885GAA 377/4885 |
| US-20190047968-A1 | 6-ACYL-1,2,4-TRIAZINE-3,5-DIONE DERIVATIVE AND HERBICIDES | DDT, AADAC, DAZAP1 | MAPT 3711/4885ALDH1A1 144/4885GAA 657/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.