Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCH | P24723 | 6/20 | 0.45 |
| ▸ | PRKCE | Q02156 | 6/20 | 0.45 |
| ▸ | PRKCD | Q05655 | 6/20 | 0.45 |
| ▸ | PRKCQ | Q04759 | 5/20 | 0.45 |
| ▸ | PRKCA | P17252 | 4/20 | 0.45 |
| ▸ | PRKCB | P05771 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.39 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3325764 | 0.88 | PRKCD (0.57) | PRKCHPRKCEPRKCDPRKCQPRKCA | |
| SCHEMBL29634278 | 0.88 | PRKCD (0.57) | PRKCHPRKCEPRKCDPRKCQPRKCA | |
| Ammonia Solution, Strong SCHEMBL19611956 | 0.78 | PRKCD (0.56) | PRKCHPRKCEPRKCDPRKCQPRKCA | |
| SCHEMBL11368186 | 0.76 | CYP19A1 (0.51) | CYP1A2CYP19A1CYP2A6HSP90AA1HSP90AB1 | |
| SCHEMBL3327832 | 0.75 | PRKCD (0.55) | PRKCHPRKCEPRKCDPRKCQPRKCA | |
| SCHEMBL3325696 | 0.72 | PRKCD (0.52) | PRKCHPRKCEPRKCDPRKCQPRKCA | |
| SCHEMBL3325907 | 0.71 | PRKCH (0.60) | PRKCHPRKCEPRKCDPRKCQPRKCA | |
| SCHEMBL3325795 | 0.70 | PRKCD (0.50) | PRKCHPRKCEPRKCDPRKCQPRKCA | |
| SCHEMBL15544680 | 0.69 | PRKCH (0.55) | PRKCHPRKCEPRKCDPRKCQPRKCA | |
| SCHEMBL3322844 | 0.69 | PRKCD (0.54) | PRKCHPRKCEPRKCDPRKCQPRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100130469-A1 | 2, 6-NAPHTHRIDINE DERIVATIVES | VAN EIS MAURICE | 2010-05-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100130469-A1 | 2, 6-NAPHTHRIDINE DERIVATIVES | PKN1, PKN2, CDK9 | PRKCH 22/4885PRKCE 18/4885PRKCD 63/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.