SCHEMBL333060

SCHEMBL333060

CCC(=O)CC(=O)CC(=O)O.[Zr]

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 2/20 0.47
TDP1 Q9NUW8 2/20 0.47
LDHA P00338 1/20 0.42
SRR Q9GZT4 1/20 0.42
HDAC3 O15379 1/20 0.35
HDAC1 Q13547 1/20 0.35
HDAC2 Q92769 1/20 0.35
HDAC8 Q9BY41 1/20 0.35
ALDH1A1 P00352 1/20 0.33
KDM4E B2RXH2 1/20 0.33
KDM6B O15054 1/20 0.33
KDM5C P41229 1/20 0.33
EGLN1 Q9GZT9 1/20 0.33
PHF8 Q9UPP1 1/20 0.33
KDM2A Q9Y2K7 1/20 0.33
MAPT P10636 1/20 0.31
KMT2A Q03164 1/20 0.31
AKR1B1 P15121 1/20 0.31
HSD11B1 P28845 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1142940 0.97 TDP1 (0.50) FFAR3TDP1LDHASRRHDAC3
SCHEMBL1170592 0.94 FFAR3 (0.47) FFAR3TDP1LDHASRRHDAC3
SCHEMBL9125434 0.94 FFAR3 (0.47) FFAR3TDP1LDHASRRHDAC3
SCHEMBL28026337 0.94
SCHEMBL24358 0.91
Ammonia Solution, Strong SCHEMBL14935458 0.88
SCHEMBL527721 0.88
SCHEMBL10956057 0.88
SCHEMBL17106050 0.88
SCHEMBL28935585 0.88 TDP1 (0.53) FFAR3TDP1LDHASRRHDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1871824-B1 COMPOUNDING SILICA-REINFORCED RUBBER WITH LOW VOLATILE ORGANIC COMPOUND (VOC) EMISSION BRIDGESTONE CORP (JP) 2017-03-01 EP claimed
US-9403969-B2 Compounding silica-reinforced rubber with low volatile organic compound (VOC) emission BRIDGESTONE CORPORATION (JP) 2016-08-02 US claimed
US-20140011924-A1 COMPOUNDING SILICA-REINFORCED RUBBER WITH LOW VOLATILE ORGANIC COMPOUND (VOC) EMISSION BRIDGESTONE CORPORATION (JP) 2014-01-09 US claimed
US-8288474-B2 Compounding silica-reinforced rubber with low volatile organic compound (VOC) emission BRIDGESTONE CORPORATION (JP) 2012-10-16 US claimed
US-8097674-B2 Amino alkoxy-modified silsesquioxanes in silica-filled rubber with low volatile organic chemical evolution BRIDGESTONE CORPORATION (JP) 2012-01-17 US claimed
US-20110180195-A1 COMPOUNDING SILICA-REINFORCED RUBBER WITH LOW VOLATILE ORGANIC COMPOUND (VOC) EMISSION BRIDGESTONE CORPORATION (JP) 2011-07-28 US claimed
US-7799870-B2 Compounding silica-reinforced rubber with low volatile organic compound (VOC) emission BRIDGESTONE CORPORATION (JP) 2010-09-21 US claimed
US-20100071818-A1 AMINO ALKOXY-MODIFIED SILSESQUIOXANES IN SILICA-FILLED RUBBER WITH LOW VOLATILE ORGANIC CHEMICAL EVOLUTION BRIDGESTONE CORPORATION (JP) 2010-03-25 US claimed
EP-1871824-A1 COMPOUNDING SILICA-REINFORCED RUBBER WITH LOW VOLATILE ORGANIC COMPOUND (VOC) EMISSION Bridgestone Corporation (JP) 2008-01-02 EP claimed
WO-2006102518-A1 COMPOUNDING SILICA-REINFORCED RUBBER WITH LOW VOLATILE ORGANIC COMPOUND (VOC) EMISSION BRIDGESTONE CORPORATION (JP) 2006-09-28 WO claimed
US-20060217473-A1 Compounding silica-reinforced rubber with low volatile organic compound (VOC) emission BRIDGESTONE CORPORATION (JP) 2006-09-28 US claimed
EP-3328919-B1 PROCESSES FOR PREPARING FUNCTIONALIZED POLYMERS, RELATED FUNCTIONALIZING COMPOUND AND PREPARATION THEREOF BRIDGESTONE CORP (JP) 2021-03-10 EP disclosed
CN-108026280-B Process for preparing functionalized polymers, related functionalized compounds and preparation thereof 株式会社普利司通 2020-11-20 CN disclosed
EP-2379773-B1 CMAS MITIGATION COMPOSITIONS, ENVIRONMENTAL BARRIER COATINGS COMPRISING THE SAME, AND CERAMIC COMPONENTS COMPRISING THE SAME GEN ELECTRIC (US) 2020-10-28 EP disclosed
US-10730961-B2 Processes for preparing functionahzed polymers, related functionalizing compound and preparation thereof BRIDGESTONE CORPORATION (JP) 2020-08-04 US disclosed
US-20100159151-A1 METHODS FOR MAKING ENVIRONMENTAL BARRIER COATINGS AND CERAMIC COMPONENTS HAVING CMAS MITIGATION CAPABILITY GENERAL ELECTRIC COMPANY 2010-06-24 US disclosed
US-20100071818-A1 AMINO ALKOXY-MODIFIED SILSESQUIOXANES IN SILICA-FILLED RUBBER WITH LOW VOLATILE ORGANIC CHEMICAL EVOLUTION BRIDGESTONE CORPORATION (JP) 2010-03-25 US disclosed
EP-1871824-A1 COMPOUNDING SILICA-REINFORCED RUBBER WITH LOW VOLATILE ORGANIC COMPOUND (VOC) EMISSION Bridgestone Corporation (JP) 2008-01-02 EP disclosed
WO-2006102518-A1 COMPOUNDING SILICA-REINFORCED RUBBER WITH LOW VOLATILE ORGANIC COMPOUND (VOC) EMISSION BRIDGESTONE CORPORATION (JP) 2006-09-28 WO disclosed
US-20060217473-A1 Compounding silica-reinforced rubber with low volatile organic compound (VOC) emission BRIDGESTONE CORPORATION (JP) 2006-09-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060217473-A1 Compounding silica-reinforced rubber with low volatile organic compound (VOC) emission OR51E2, RIF1, SRMS FFAR3 2616/4885TDP1 1993/4885LDHA 2837/4885
US-10730961-B2 Processes for preparing functionahzed polymers, related functionalizing compound and preparation thereof PFAS, ESD, F9 FFAR3 2036/4885TDP1 3687/4885LDHA 2726/4885
US-20110180195-A1 COMPOUNDING SILICA-REINFORCED RUBBER WITH LOW VOLATILE ORGANIC COMPOUND (VOC) EMISSION OR51E2, RIF1, SRMS FFAR3 2616/4885TDP1 1993/4885LDHA 2837/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.