Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Erythromycin Propionate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 9/20 | 1.00 |
| ▸ | SLCO1B3 | Q9NPD5 | 3/20 | 1.00 |
| ▸ | SLCO1B1 | Q9Y6L6 | 3/20 | 1.00 |
| ▸ | USP2 | O75604 | 3/20 | 1.00 |
| ▸ | ABCB11 | O95342 | 2/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 2/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 1.00 |
| ▸ | TP53 | P04637 | 1/20 | 1.00 |
| ▸ | MAPT | P10636 | 1/20 | 1.00 |
| ▸ | HPGD | P15428 | 1/20 | 1.00 |
| ▸ | ALOX12 | P18054 | 1/20 | 1.00 |
| ▸ | RECQL | P46063 | 1/20 | 1.00 |
| ▸ | BLM | P54132 | 1/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 1/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 1.00 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.86 |
| ▸ | PGR | P06401 | 1/20 | 0.84 |
| ▸ | HTR1A | P08908 | 1/20 | 0.84 |
| ▸ | DRD1 | P21728 | 1/20 | 0.84 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.84 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Erythromycin Propionate SCHEMBL29400629 | 1.00 | CYP3A4 (1.00) | CYP3A4SLCO1B3SLCO1B1USP2ABCB11 | |
| Erythromycin Propionate SCHEMBL25223334 | 1.00 | CYP3A4 (1.00) | CYP3A4SLCO1B3SLCO1B1USP2ABCB11 | |
| Erythromycin Propionate SCHEMBL23124754 | 0.97 | CYP3A4 (0.95) | CYP3A4SLCO1B3SLCO1B1USP2ABCB11 | |
| Erythromycin Propionate SCHEMBL343123 | 0.97 | CYP3A4 (0.94) | CYP3A4SLCO1B3SLCO1B1USP2ABCB11 | |
| Erythromycin Ethylsuccinate SCHEMBL28122248 | 0.96 | CYP3A4 (0.92) | CYP3A4SLCO1B3SLCO1B1USP2ABCB11 | |
| Erythromycin SCHEMBL11319266 | 0.93 | ABCB11 (1.00) | CYP3A4SLCO1B3SLCO1B1USP2ABCB11 | |
| Erythromycin SCHEMBL11319270 | 0.93 | ABCB11 (1.00) | CYP3A4SLCO1B3SLCO1B1USP2ABCB11 | |
| Erythromycin SCHEMBL7597003 | 0.93 | ABCB11 (1.00) | CYP3A4SLCO1B3SLCO1B1USP2ABCB11 | |
| Erythromycin SCHEMBL7597008 | 0.93 | ABCB11 (1.00) | CYP3A4SLCO1B3SLCO1B1USP2ABCB11 | |
| Erythromycin SCHEMBL3473986 | 0.92 | ABCB11 (0.95) | CYP3A4SLCO1B3SLCO1B1USP2ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 8590 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122084113-A | High-time-frequency earth surface temperature anomaly detection and correction method and detection and correction device | — | 2026-05-26 | — | — | CN | claimed |
| CN-122067090-A | Aquatic plant identification method, aquatic plant identification device, electronic equipment, storage medium and product | 中国长江三峡集团有限公司 | 2026-05-19 | — | — | CN | claimed |
| CN-122066604-A | Self-supervision remote sensing image stripe noise suppression method and system based on frequency domain structure priori | 东北林业大学 | 2026-05-19 | — | — | CN | claimed |
| CN-119620076-B | Laplacian operator-based distributed scatterer InSAR phase enhancement method | 中国矿业大学 | 2026-05-15 | — | — | CN | claimed |
| CN-122017841-A | Physical-guided space deep learning forest canopy height inversion method | 西南林业大学 | 2026-05-12 | — | — | CN | claimed |
| EP-4002821-B1 | UNIFORMITY COMPENSATION REFINEMENT MECHANISM | RICOH CO LTD (JP) | 2026-04-01 | — | — | EP | claimed |
| EP-4236476-B1 | SIGNAL TRANSMISSION METHOD, NETWORK DEVICE, TERMINAL AND STORAGE MEDIUM | Datang mobile communications equipment co ltd (CN) | 2026-04-01 | — | — | EP | claimed |
| WO-2025242416-A1 | LIGHT-EMITTING DEVICE HAVING INGAALP PASSIVATION, AND METHOD OF MANUFACTURING | AMS-OSRAM INTERNATIONAL GMBH (DE) | 2025-11-27 | — | — | WO | claimed |
| US-20250249110-A1 | ANTIMICROBIAL PEPTIDE DERIVATIVE AND USE THEREOF | SICHUAN UNIVERSITY (CN) | 2025-08-07 | — | — | US | claimed |
| US-20250228841-A1 | COMPOSITIONS AFFECTING PIGMENT PRODUCTION AND METHODS FOR TREATMENT OF BACTERIAL DISEASES | APTORUM THERAPEUTICS LTD (HK) | 2025-07-17 | — | — | US | claimed |
| CN-1031326-A | Method with haloplankton as living drug carrier control fish and shrimp diseases | QINGDAO OCEAN UNIVERSITY (CN) | 1989-03-01 | — | — | CN | claimed |
| US-4783337-A | Osmotic system comprising plurality of members for dispensing drug | ALZA CORPORATION (US) | 1988-11-08 | — | — | US | claimed |
| EP-0109102-B1 | STORAGE STABLE TOPICAL PHARMACEUTICAL COMPOSITION INCLUDING NITROGEN-CONTAINING STABILIZERS | THE PROCTER & GAMBLE COMPANY (US) | 1988-01-20 | — | — | EP | claimed |
| EP-0109102-A2 | Storage stable topical pharmaceutical composition including nitrogen-containing stabilizers | THE PROCTER & GAMBLE COMPANY (US) | 1984-05-23 | — | — | EP | claimed |
| EP-0027286-B1 | ANTI-ACNE COMPOSITION COMPRISING DIISOPROPYL SEBACATE | THE PROCTER & GAMBLE COMPANY (US) | 1984-02-08 | — | — | EP | claimed |
| US-4299826-A | TOPICAL APPLICATION OF ERYTHROMYCIN OR DERIVATIVES | THE PROCTER & GAMBLE COMPANY (US) | 1981-11-10 | — | — | US | claimed |
| EP-0001871-B1 | AN ERYTHROMYCIN COMPOUND, A PROCESS FOR PREPARING THE COMPOUND AND COMPOSITIONS CONTAINING THE COMPOUND USEFUL IN THE TREATMENT OF ACNE | THE PROCTER & GAMBLE COMPANY (US) | 1981-07-29 | — | — | EP | claimed |
| EP-0027286-A2 | Anti-acne composition comprising diisopropyl sebacate | THE PROCTER & GAMBLE COMPANY (US) | 1981-04-22 | — | — | EP | claimed |
| US-4261982-A | ZINC ERYTHROMYCIN FOR ACNE | THE PROCTER & GAMBLE COMPANY (US) | 1981-04-14 | — | — | US | claimed |
| EP-0001871-A1 | An erythromycin compound, a process for preparing the compound and compositions containing the compound useful in the treatment of acne | THE PROCTER & GAMBLE COMPANY (US) | 1979-05-16 | — | — | EP | claimed |