Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | APEX1 | P27695 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA3 | P07451 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23272826 | 0.89 | CA12 (0.53) | POLBAPEX1HPGDCA12CA1 | |
| SCHEMBL9878198 | 0.85 | CA12 (0.46) | POLBAPEX1HPGDCA12CA1 | |
| SCHEMBL1478637 | 0.84 | DGAT1 (0.47) | POLBAPEX1HPGDCA12CA1 | |
| SCHEMBL14453581 | 0.84 | CA12 (0.44) | POLBAPEX1HPGDCA12CA1 | |
| SCHEMBL2478225 | 0.84 | CA12 (0.49) | POLBAPEX1HPGDCA12CA1 | |
| SCHEMBL11479346 | 0.83 | CA12 (0.59) | HPGDCA12CA1CA2CA3 | |
| SCHEMBL5327199 | 0.82 | DGAT1 (0.48) | POLBAPEX1HPGDCA12CA1 | |
| SCHEMBL8055152 | 0.81 | POLB (0.55) | POLBAPEX1HPGDTSHRMAPT | |
| SCHEMBL31124522 | 0.80 | CA12 (0.63) | HPGDCA12CA1CA2CA3 | |
| SCHEMBL31124523 | 0.80 | CA12 (0.63) | HPGDCA12CA1CA2CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1009920-B | Halogenated benzoic acid derivatives and their preparation | KYORIN SEIYAKU KK (JP) | 1990-10-10 | — | — | CN | claimed |
| CN-87100373-A | Halogenated benzoic acid derivative and preparation thereof | — | 1987-08-19 | — | — | CN | claimed |
| US-8592452-B2 | Cyclic amine compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-11-26 | — | — | US | disclosed |
| US-8247452-B2 | Urea- and urethane-substituted acylureas, process for their preparation and their use | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2012-08-21 | — | — | US | disclosed |
| US-20100152236-A1 | Cyclic amine compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-17 | — | — | US | disclosed |
| EP-1590322-B1 | CARBONYL-AMINO SUBSTITUTED ACYL PHENYL UREA DERIVATIVES, METHOD FOR THE PRODUCTION AND USE THEREOF | SANOFI AVENTIS DEUTSCHLAND (DE) | 2009-09-23 | — | — | EP | disclosed |
| EP-1523471-B1 | UREA-SUBSTITUTED AND URETHANE-SUBSTITUTED ACYLUREAS, METHODS FOR THE PRODUCTION THEREOF AND THEIR USE AS MEDICAMENTS | SANOFI AVENTIS DEUTSCHLAND (DE) | 2009-09-16 | — | — | EP | disclosed |
| EP-1911743-A1 | CYCLIC AMINE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2008-04-16 | — | — | EP | disclosed |
| US-20080051419-A1 | AMINE DERIVATIVES USEFUL AS ANTICANCER AGENTS | PFIZER INC. | 2008-02-28 | — | — | US | disclosed |
| US-20080033042-A1 | UREA-AND URETHANE-SUBSTITUTED ACYLUREAS, PROCESS FOR THEIR PREPARATION AND THEIR USE | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2008-02-07 | — | — | US | disclosed |
| US-7262220-B2 | Urea- and urethane-substituted acylureas, process for their preparation and their use | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2007-08-28 | — | — | US | disclosed |
| US-20040102518-A1 | N-benzoylureidocinnamic acid derivatives, processes for preparing them and their use | AVENTIS PHARMA AG (DE) | 2004-05-27 | — | — | US | disclosed |
| US-20040087659-A1 | Urea- and urethane-substituted acylureas, process for their preparation and their use | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2004-05-06 | — | — | US | disclosed |
| WO-2004007437-A1 | UREA-SUBSTITUTED AND URETHANE-SUBSTITUTED ACYLUREAS, METHODS FOR THE PRODUCTION THEREOF AND THEIR USE AS MEDICAMENTS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-01-22 | — | — | WO | disclosed |
| WO-2003104188-A1 | N-BENZOYLUREIDOCINNAMATE DERIVATIVES, METHOD FOR PRODUCTION AND USE THEREOF | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2003-12-18 | — | — | WO | disclosed |
| CN-1009920-B | Halogenated benzoic acid derivatives and their preparation | KYORIN SEIYAKU KK (JP) | 1990-10-10 | — | — | CN | disclosed |
| CN-1008732-B | Benzoyl acetate derivative and preparation method thereof | KYORIN SEIYAKU KK (JP) | 1990-07-11 | — | — | CN | disclosed |
| CN-87100382-A | Benzoylacetic acid ester derivatives and preparation method thereof | — | 1987-09-02 | — | — | CN | disclosed |
| CN-87100373-A | Halogenated benzoic acid derivative and preparation thereof | — | 1987-08-19 | — | — | CN | disclosed |
| CN-87100387-A | Process for preparing quinolone carboxylic acid derivatives | — | 1987-08-19 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040102518-A1 | N-benzoylureidocinnamic acid derivatives, processes for preparing them and their use | SLC5A1, NQO1, SLC5A2 | POLB 2502/4885APEX1 382/4885HPGD 76/4885 |
| US-20040087659-A1 | Urea- and urethane-substituted acylureas, process for their preparation and their use | UGP2, UGDH, UGT1A1 | POLB 2016/4885APEX1 577/4885HPGD 996/4885 |
| US-20100152236-A1 | Cyclic amine compound | AR, FSHR, NR5A1 | POLB 3355/4885APEX1 908/4885HPGD 1757/4885 |
| US-20080033042-A1 | UREA-AND URETHANE-SUBSTITUTED ACYLUREAS, PROCESS FOR THEIR PREPARATION AND THEIR USE | UGP2, UGDH, UMPS | POLB 2082/4885APEX1 826/4885HPGD 918/4885 |
| US-20080051419-A1 | AMINE DERIVATIVES USEFUL AS ANTICANCER AGENTS | CCNY, CCND2, CCND1 | POLB 2462/4885APEX1 1895/4885HPGD 1958/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.