Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | APEX1 | P27695 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 3/20 | 0.43 |
| ▸ | CES1 | P23141 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8064637 | 0.84 | CES2 (0.50) | POLBAPEX1HPGDMAPTTSHR | |
| SCHEMBL32668944 | 0.83 | KEAP1 (0.55) | POLBAPEX1HPGDMAPTTSHR | |
| SCHEMBL3820327 | 0.83 | POLB (0.53) | POLBAPEX1HPGDMAPTTSHR | |
| SCHEMBL7744978 | 0.83 | POLB (0.53) | POLBAPEX1HPGDMAPTTSHR | |
| SCHEMBL979056 | 0.83 | KEAP1 (0.55) | POLBAPEX1HPGDMAPTTSHR | |
| Hydrochloric Acid SCHEMBL9488278 | 0.81 | KEAP1 (0.53) | POLBAPEX1HPGDMAPTTSHR | |
| SCHEMBL3333144 | 0.81 | POLB (0.52) | POLBAPEX1HPGDMAPTTSHR | |
| SCHEMBL3621616 | 0.81 | POLB (0.56) | POLBAPEX1HPGDMAPTTSHR | |
| SCHEMBL9516561 | 0.78 | ALDH1A1 (0.55) | POLBAPEX1HPGDMAPTTSHR | |
| SCHEMBL9518683 | 0.78 | POLB (0.49) | POLBAPEX1HPGDMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0596395-B1 | Process for the preparation of fluorinated benzil | CLARIANT GMBH (DE) | 2000-06-28 | — | — | EP | disclosed |
| US-5463135-A | Fluorinated benzils and a process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0596395-A1 | Fluorinated benzils and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-05-11 | — | — | EP | disclosed |