SCHEMBL3333221

SCHEMBL3333221

C[C@@H](NC(=O)N1C(=O)C(Cc2ccnc(N)c2)C1C(=O)OC(=O)C(F)(F)F)c1cccc2ccccc12

nearest known ligand 0.48

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F11 P03951 20/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3336488 1.00 F11 (0.48) F11
Trifluoroacetic Acid SCHEMBL3336479 0.89 F11 (0.58) F11
Trifluoroacetic Acid SCHEMBL3333215 0.89 F11 (0.58) F11
SCHEMBL3336142 0.88 F11 (0.55) F11
SCHEMBL3335125 0.88 F11 (0.55) F11
SCHEMBL3336681 0.87 F11 (0.43) F11
SCHEMBL3963729 0.85 F11 (0.42) F11
Trifluoroacetic Acid SCHEMBL3336675 0.85 F11 (0.46) F11
SCHEMBL20303325 0.85 F11 (0.52) F11
SCHEMBL20319023 0.85 F11 (0.52) F11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100144698-A1 SUBSTITUTED AZETIDINONES DAIAMED (US) 2010-06-10 US disclosed
US-20090143351-A1 SUBSTITUTED AZETIDINONES DAIAMED (US) 2009-06-04 US disclosed
US-7501404-B2 Substituted azetidinones DAIMED (US) 2009-03-10 US disclosed
US-20070105832-A1 Substituted azetidinones Cadrenal Therapeutics, Inc. 2007-05-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070105832-A1 Substituted azetidinones F2R, CPA3, CFD F11 17/4885
US-20100144698-A1 SUBSTITUTED AZETIDINONES F2R, CPA3, CFD F11 17/4885
US-20090143351-A1 SUBSTITUTED AZETIDINONES F2R, CPA3, CFD F11 17/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.