Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 8/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13034149 | 0.86 | MEN1 (0.58) | CYP3A4ALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL7092605 | 0.84 | CYP3A4 (0.56) | CA2CYP3A4ALDH1A1CA1MEN1 | |
| SCHEMBL11462792 | 0.83 | CA2 (0.51) | CA2ALDH1A1CA1MEN1KMT2A | |
| SCHEMBL13034159 | 0.83 | CYP3A4 (0.51) | CA2CYP3A4ALDH1A1MEN1KMT2A | |
| SCHEMBL27768097 | 0.81 | CYP3A4 (0.52) | CA2CYP3A4ALDH1A1MEN1KMT2A | |
| SCHEMBL17655539 | 0.81 | ESR1 (0.55) | CA2CYP3A4ALDH1A1CA1 | |
| SCHEMBL29074791 | 0.80 | ALDH1A1 (0.50) | CA2CYP3A4ALDH1A1MEN1KMT2A | |
| SCHEMBL27666258 | 0.80 | CYP3A4 (0.53) | CA2CYP3A4ALDH1A1MEN1KMT2A | |
| SCHEMBL13434033 | 0.80 | CYP3A4 (0.49) | CA2CYP3A4ALDH1A1MEN1KMT2A | |
| SCHEMBL27666267 | 0.80 | CYP3A4 (0.53) | CA2CYP3A4ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8404836-B2 | 3-phenyl acrylic acid compound activators of type PPAR receptors and pharmaceutical/cosmetic compositions comprised thereof | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2013-03-26 | — | — | US | disclosed |
| US-20100144884-A1 | NOVEL 3-PHENYL ACRYLIC ACID COMPOUND ACTIVATORS OF TYPE PPAR RECEPTORS AND PHARMACEUTICAL/COSMETIC COMPOSITIONS COMPRISED THEREOF | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2010-06-10 | — | — | US | disclosed |
| CN-101679228-A | Novel 3-phenylacrylic acid derivatives as activators of receptors of the PPAR type, method for preparing same and use thereof in cosmetic or pharmaceutical compositions | JEAN-GUY BOITEAU | 2010-03-24 | — | — | CN | disclosed |
| CN-1984894-A | Compounds and compositions as PPAR modulators | IRM LLC (BM) | 2007-06-20 | — | — | CN | disclosed |
| CN-1980919-A | Compounds and compositions as ppar modulators | IRM LLC (BM) | 2007-06-13 | — | — | CN | disclosed |
| CN-1980906-A | Compounds and compositions as PPAR modulators | IRM LLC (BM) | 2007-06-13 | — | — | CN | disclosed |
| CN-1980894-A | Compounds and compositions as PPAR modulators | IRM LLC (BM) | 2007-06-13 | — | — | CN | disclosed |
| US-4588835-A | Process for preparing alkoxyphenols | OTSUKA KAGAKU YAKUHIN KABUSHIKI KAISHA (JP) | 1986-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100144884-A1 | NOVEL 3-PHENYL ACRYLIC ACID COMPOUND ACTIVATORS OF TYPE PPAR RECEPTORS AND PHARMACEUTICAL/COSMETIC COMPOSITIONS COMPRISED THEREOF | PPARG, PPARA, PPARD | CA2 4415/4885CYP3A4 1505/4885ALDH1A1 372/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.