Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL437174 | 0.72 | TDP1 (0.41) | HIF1AALDH1A1TSHRLMNATDP1 | |
| SCHEMBL13116623 | 0.69 | TSHR (0.47) | HIF1AALDH1A1CHRNB4CHRNA3TSHR | |
| SCHEMBL19243529 | 0.69 | TSHR (0.56) | ALDH1A1CHRNB4CHRNA3TSHRLMNA | |
| SCHEMBL19207373 | 0.69 | TSHR (0.56) | ALDH1A1CHRNB4CHRNA3TSHRLMNA | |
| SCHEMBL22898429 | 0.66 | TSHR (0.47) | HIF1AALDH1A1CHRNB4CHRNA3TSHR | |
| SCHEMBL451767 | 0.66 | CHRNB4 (0.54) | HIF1AALDH1A1CHRNB4CHRNA3TSHR | |
| Dinitrophenylene SCHEMBL27724274 | 0.65 | TSHR (0.77) | ALDH1A1TSHRLMNAHSP90AA1TDP1 | |
| SCHEMBL30522666 | 0.65 | TSHR (0.56) | HIF1AALDH1A1CHRNB4CHRNA3TSHR | |
| SCHEMBL28092025 | 0.65 | CHRNB4 (0.67) | HIF1AALDH1A1CHRNB4CHRNA3TSHR | |
| SCHEMBL31220888 | 0.65 | TSHR (0.56) | HIF1AALDH1A1CHRNB4CHRNA3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081884-B1 | PROCESS FOR THE PREPARATION OF AMINES | SYNGENTA PARTICIPATIONS AG (CH) | 2013-05-22 | — | — | EP | disclosed |
| US-20100145100-A1 | PROCESS FOR THE PREPARATION OF AMINES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-06-10 | — | — | US | disclosed |
| EP-2081884-A1 | PROCESS FOR THE PREPARATION OF AMINES | Syngeta Participations AG (CH) | 2009-07-29 | — | — | EP | disclosed |
| WO-2008037460-A1 | PROCESS FOR THE PREPARATION OF AMINES. | SYNGENTA PARTICIPATIONS AG (CH) | 2008-04-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100145100-A1 | PROCESS FOR THE PREPARATION OF AMINES | SNCA, SYNJ1, PARK7 | HIF1A 1424/4885ALDH1A1 1570/4885CHRNB4 742/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.