Sugi Predict

Sugi Predict / Compounds / SCHEMBL437174

SCHEMBL437174

SCHEMBL437174

CC(C)=C1C2C=CC1c1c2cccc1[N+](=O)[O-]

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 4/20 0.41
▸ GPR35 Q9HC97 2/20 0.41
▸ TSHR P16473 4/20 0.38
▸ SMN1; SMN2 Q16637 3/20 0.38
▸ ERN1 O75460 1/20 0.37
▸ KDM4E B2RXH2 3/20 0.36
▸ MAPT P10636 3/20 0.36
▸ L3MBTL1 Q9Y468 2/20 0.36
▸ KMT2A Q03164 3/20 0.36
▸ MEN1 O00255 2/20 0.36
▸ POLB P06746 1/20 0.36
▸ HSD17B10 Q99714 2/20 0.36
▸ GAA P10253 2/20 0.35
▸ HTT P42858 1/20 0.35
▸ ALDH1A1 P00352 2/20 0.35
▸ LMNA P02545 2/20 0.35
▸ ABCC4 O15439 1/20 0.35
▸ PLIN1 O60240 1/20 0.35
▸ CACNA1F O60840 1/20 0.35
▸ GMNN O75496 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12385542 0.85 GPR35 (0.41) TDP1GPR35TSHRSMN1; SMN2ERN1
SCHEMBL4572430 0.84 TDP1 (0.38) TDP1GPR35TSHRSMN1; SMN2KDM4E
SCHEMBL6982116 0.75 TDP1 (0.40) TDP1GPR35TSHRSMN1; SMN2ERN1
SCHEMBL3334130 0.72 HIF1A (0.43) TDP1GPR35TSHRSMN1; SMN2KMT2A
SCHEMBL4601117 0.70 POLB (0.33) KMT2AMEN1POLBGAAMAOA
SCHEMBL469131 0.70 CUL4A (0.43) TDP1GPR35TSHRSMN1; SMN2KDM4E
SCHEMBL13369520 0.68 CHRNB2 (0.37) TDP1GPR35TSHRSMN1; SMN2ERN1
SCHEMBL14404638 0.67 NR4A1 (0.40) TDP1GPR35TSHRSMN1; SMN2ERN1
SCHEMBL12474084 0.67 NR4A1 (0.40) TDP1GPR35TSHRSMN1; SMN2ERN1
SCHEMBL14977883 0.67 TDP1 (0.38) TDP1GPR35TSHRSMN1; SMN2ERN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117362179-A Preparation method of benzovindiflupyr intermediate 9-dichloromethylene-1, 4-dihydro-5-nitro-1, 4-methanonaphthalene 浙江工业大学 2024-01-09 — — CN disclosed
US-11647749-B2 Fungicidal compositions SYNGENTA PARTICIPATIONS AG (CH) 2023-05-16 — — US disclosed
US-9878970-B1 Process for the preparation of benzonorbornenes SYNGENTA CROP PROTECTION, LLC (US) 2018-01-30 — — US disclosed
US-20180016211-A1 PROCESS FOR THE PREPARATION OF BENZONORBORNENES SYNGENTA CROP PROTECTION, LLC (US) 2018-01-18 — — US disclosed
US-9796646-B2 Process for the preparation of benzonorbornenes SYNGENTA CROP PROTECTION, LLC (US) 2017-10-24 — — US disclosed
US-20170202220-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION, LLC (US) 2017-07-20 — — US disclosed
US-9642365-B2 Fungicidal compositions SYNGENTA CROP PROTECTION, LLC (US) 2017-05-09 — — US disclosed
US-20160192655-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION, LLC (US) 2016-07-07 — — US disclosed
US-9314022-B2 Fungicidal compositions SYNGENTA CROP PROTECTION, LLC (US) 2016-04-19 — — US disclosed
US-9115043-B2 Process for the preparation of benzonorbornenes SYNGENTA CROP PROTECTION, LLC (US) 2015-08-25 — — US disclosed
US-20090163569-A1 PROCESS FOR THE PRODUCTION OF AMIDES SYNGENTA CROP PROTECTION, INC. (US) 2009-06-25 — — US disclosed
US-20090163569-A1 PROCESS FOR THE PRODUCTION OF AMIDES SYNGENTA CROP PROTECTION, INC. (US) 2009-06-25 — — US disclosed
US-20080227835-A1 Heterocyclic Amide Derivatives Useful as Microbiocides SYNGENTA CROP PROTECTION, INC. (US) 2008-09-18 — — US disclosed
US-20080227835-A1 Heterocyclic Amide Derivatives Useful as Microbiocides SYNGENTA CROP PROTECTION, INC. (US) 2008-09-18 — — US disclosed
EP-1928838-A1 PROCESS FOR THE PRODUCTION OF AMIDES Syngeta Participations AG (CH) 2008-06-11 — — EP disclosed
US-20070265267-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION, INC. (US) 2007-11-15 — — US disclosed
US-20070265267-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION, INC. (US) 2007-11-15 — — US disclosed
US-20070244121-A1 Synergistic Fungicidal Compositions SYNGENTA CROP PROTECTION, INC. (US) 2007-10-18 — — US disclosed
WO-2007048556-A1 HETEROCYCLIC AMIDE DERIVATIVES USEFUL AS MICROBIOCIDES SYNGENTA PARTICIPATIONS AG (CH) 2007-05-03 — — WO disclosed
WO-2007031323-A1 PROCESS FOR THE PRODUCTION OF AMIDES SYNGENTA PARTICIPATIONS AG. (CH) 2007-03-22 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11647749-B2 Fungicidal compositions BROX, RER1, BLVRB TDP1 1537/4885GPR35 3687/4885TSHR 2256/4885
US-20160192655-A1 FUNGICIDAL COMPOSITIONS BROX, RER1, BLVRB TDP1 1537/4885GPR35 3687/4885TSHR 2256/4885
US-20180016211-A1 PROCESS FOR THE PREPARATION OF BENZONORBORNENES CCL5, CXCR2, CXCR3 TDP1 3639/4885GPR35 3512/4885TSHR 4439/4885
US-20170202220-A1 FUNGICIDAL COMPOSITIONS BROX, RER1, BLVRB TDP1 1537/4885GPR35 3687/4885TSHR 2256/4885
US-20070265267-A1 FUNGICIDAL COMPOSITIONS CRY1, ERG28, DDT TDP1 2057/4885GPR35 4174/4885TSHR 3630/4885
US-20070244121-A1 Synergistic Fungicidal Compositions DDT, CRY1, HCN1 TDP1 1332/4885GPR35 4149/4885TSHR 3282/4885
US-20090163569-A1 PROCESS FOR THE PRODUCTION OF AMIDES C5, CFH, C9 TDP1 4754/4885GPR35 2984/4885TSHR 89/4885
US-20080227835-A1 Heterocyclic Amide Derivatives Useful as Microbiocides CBR3, CBR1, CYP8B1 TDP1 3870/4885GPR35 3375/4885TSHR 1287/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.