Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 2/20 | 0.43 |
| ▸ | LTA4H | P09960 | 6/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 2/20 | 0.36 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | BAX | Q07812 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28762127 | 0.82 | HRH1 (0.45) | LTA4H | |
| SCHEMBL3051760 | 0.78 | LTA4H (0.52) | SRD5A2LTA4HTSHRNR1H2BAX | |
| SCHEMBL4440599 | 0.77 | LTA4H (0.55) | LTA4HTSHRNR1H2BAXKDM4E | |
| SCHEMBL7474811 | 0.76 | LTA4H (0.55) | LTA4HCALM1IDH1KMT2A | |
| SCHEMBL359816 | 0.74 | LTA4H (0.42) | LTA4HTSHRNR1H2BAXKDM4E | |
| SCHEMBL28994484 | 0.74 | LTA4H (0.42) | LTA4HTSHRNR1H2BAXKDM4E | |
| SCHEMBL23098203 | 0.72 | SRD5A2 (0.70) | SRD5A2LTA4HTSHRFFAR1CALM1 | |
| SCHEMBL9906839 | 0.72 | SRD5A2 (0.70) | SRD5A2LTA4HTSHRFFAR1CALM1 | |
| SCHEMBL11686925 | 0.70 | MAPT (0.40) | LTA4HTSHRKDM4EMAPTKMT2A | |
| SCHEMBL6965984 | 0.70 | TSHR (0.40) | LTA4HTSHRGRIN1GRIN2BKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100144872-A1 | New Methylenebisphenyl Compounds Useful in the Treatment of Inflammation | BIOLIPOX AB | 2010-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100144872-A1 | New Methylenebisphenyl Compounds Useful in the Treatment of Inflammation | LTC4S, LTB4R2, LTB4R | SRD5A2 738/4885LTA4H 6/4885TSHR 1657/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.