Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | HPGD | P15428 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 5/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.61 |
| ▸ | NPC1 | O15118 | 4/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | TP53 | P04637 | 3/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | APP | P05067 | 1/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.61 |
| ▸ | SNCA | P37840 | 1/20 | 0.61 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.61 |
| ▸ | RELA | Q04206 | 1/20 | 0.61 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9032997 | 0.98 | ALDH1A1 (0.62) | ALDH1A1HPGDMEN1KMT2AKDM4E | |
| SCHEMBL9033307 | 0.93 | ALDH1A1 (0.61) | ALDH1A1HPGDMEN1KMT2AKDM4E | |
| SCHEMBL3333026 | 0.90 | KDM4E (0.61) | ALDH1A1HPGDMEN1KMT2AKDM4E | |
| SCHEMBL5761334 | 0.90 | ALDH1A1 (0.68) | ALDH1A1HPGDMEN1KMT2AKDM4E | |
| SCHEMBL22955330 | 0.90 | KDM4E (0.71) | ALDH1A1HPGDMEN1KMT2AKDM4E | |
| SCHEMBL15245092 | 0.90 | KDM4E (0.71) | ALDH1A1HPGDMEN1KMT2AKDM4E | |
| SCHEMBL10380499 | 0.90 | ALDH1A1 (0.54) | ALDH1A1HPGDMEN1KMT2AKDM4E | |
| SCHEMBL7394693 | 0.90 | KDM4E (0.54) | ALDH1A1HPGDMEN1KMT2AKDM4E | |
| SCHEMBL3335842 | 0.89 | KDM4E (0.76) | ALDH1A1HPGDMEN1KMT2AKDM4E | |
| SCHEMBL1171146 | 0.88 | ALDH1A1 (0.53) | ALDH1A1HPGDMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997012613-A1 | METHOD FOR TREATING AND PREVENTING INFLAMMATION AND ATHEROSCLEROSIS | WARNER-LAMBERT COMPANY (US) | 1997-04-10 | — | — | WO | claimed |
| CN-104817697-B | A kind of branched polyphenylene sulfide copolymer and preparation method thereof containing condensed-nuclei aromatics | 常州大学 | 2018-10-19 | — | — | CN | disclosed |
| CN-104744697-B | Polyphenylene sulfide copolymer containing p-phenyl dibenzyl structural unit and preparation method for polyphenylene sulfide copolymer | 常州大学 | 2017-05-24 | — | — | CN | disclosed |
| US-8198307-B2 | Imidazole derivatives having aryl piperidine substituent, method for preparation thereof and pharmaceutical compositions containing same | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2012-06-12 | — | — | US | disclosed |
| US-20100145054-A1 | IMIDAZOLE DERIVATIVES HAVING ARYL PIPERIDINE SUBSTITUENT, METHOD FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2010-06-10 | — | — | US | disclosed |
| CN-101402731-A | Polyphenylene sulfide copolymer containing aromatic heterocycle, preparation method, application and product thereof | DEYANG KEJI NEW MATERIAL CO LT (CN) | 2009-04-08 | — | — | CN | disclosed |
| US-6001866-A | ADMINISTERING A COMPOUND WHICH IS AN INHIBITOR OF THE ENZYME 15-LIPOXYGENASE (15-LO). | WARNER-LAMBERT COMPANY (US) | 1999-12-14 | — | — | US | disclosed |
| US-5972980-A | ADMINISTERING AN LIPOXYGENASE INHIBITOR | WARNER-LAMBERT COMPANY (US) | 1999-10-26 | — | — | US | disclosed |
| WO-1997012613-A1 | METHOD FOR TREATING AND PREVENTING INFLAMMATION AND ATHEROSCLEROSIS | WARNER-LAMBERT COMPANY (US) | 1997-04-10 | — | — | WO | disclosed |
| EP-0511187-B1 | Process for the preparation of 1H-benzimidazoles | UCB SA (BE) | 1996-11-20 | — | — | EP | disclosed |
| EP-0511187-A1 | Process for the preparation of 1H-benzimidazoles | U C B, S.A. (BE) | 1992-10-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100145054-A1 | IMIDAZOLE DERIVATIVES HAVING ARYL PIPERIDINE SUBSTITUENT, METHOD FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | TYR, MCHR1, MCHR2 | ALDH1A1 448/4885HPGD 527/4885MEN1 163/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.