Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | HPGD | P15428 | 4/20 | 0.61 |
| ▸ | NPC1 | O15118 | 4/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | TP53 | P04637 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | APP | P05067 | 1/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.61 |
| ▸ | SNCA | P37840 | 1/20 | 0.61 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.61 |
| ▸ | RELA | Q04206 | 1/20 | 0.61 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7187637 | 0.93 | ALDH1A1 (0.68) | ALDH1A1HPGDNPC1KDM4ERAB9A | |
| SCHEMBL3335014 | 0.93 | ALDH1A1 (0.61) | ALDH1A1HPGDNPC1KDM4ERAB9A | |
| SCHEMBL9032997 | 0.91 | ALDH1A1 (0.62) | ALDH1A1HPGDNPC1KDM4ERAB9A | |
| SCHEMBL20445296 | 0.91 | NPC1 (0.60) | ALDH1A1HPGDNPC1KDM4ERAB9A | |
| SCHEMBL7186585 | 0.87 | ALDH1A1 (0.49) | ALDH1A1HPGDNPC1KDM4ERAB9A | |
| SCHEMBL3337505 | 0.86 | ALDH1A1 (0.55) | ALDH1A1HPGDNPC1KDM4ERAB9A | |
| SCHEMBL2246334 | 0.86 | ALDH1A1 (0.77) | ALDH1A1HPGDNPC1KDM4ERAB9A | |
| SCHEMBL3336522 | 0.86 | NPC1 (0.57) | ALDH1A1HPGDNPC1KDM4ERAB9A | |
| SCHEMBL3337292 | 0.86 | GUSB (0.57) | ALDH1A1HPGDNPC1KDM4ERAB9A | |
| SCHEMBL2094029 | 0.86 | ALDH1A1 (0.55) | ALDH1A1HPGDNPC1KDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511187-B1 | Process for the preparation of 1H-benzimidazoles | UCB SA (BE) | 1996-11-20 | — | — | EP | disclosed |
| EP-0511187-A1 | Process for the preparation of 1H-benzimidazoles | U C B, S.A. (BE) | 1992-10-28 | — | — | EP | disclosed |