SCHEMBL3335842

SCHEMBL3335842

Clc1ccc2[nH]c(-c3ccccc3)nc2c1

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 9/20 0.76
▸ ALDH1A1 P00352 8/20 0.76
▸ HPGD P15428 6/20 0.76
▸ HSD17B10 Q99714 5/20 0.76
▸ MAPT P10636 4/20 0.76
▸ MEN1 O00255 4/20 0.76
▸ KMT2A Q03164 4/20 0.76
▸ TP53 P04637 4/20 0.76
▸ CYP3A4 P08684 1/20 0.76
▸ MAPK1 P28482 1/20 0.76
▸ FTO Q9C0B1 1/20 0.76
▸ NPC1 O15118 8/20 0.62
▸ RAB9A P51151 7/20 0.62
▸ GAA P10253 3/20 0.62
▸ SMN1; SMN2 Q16637 6/20 0.53
▸ GLA P06280 1/20 0.53
▸ HTT P42858 1/20 0.53
▸ GFER P55789 1/20 0.53
▸ RCE1 Q9Y256 1/20 0.53
▸ LMNA P02545 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22955330 0.97 KDM4E (0.71) KDM4EALDH1A1HPGDHSD17B10MAPT
SCHEMBL15245092 0.97 KDM4E (0.71) KDM4EALDH1A1HPGDHSD17B10MAPT
SCHEMBL9032997 0.91 ALDH1A1 (0.62) KDM4EALDH1A1HPGDHSD17B10MAPT
SCHEMBL22956059 0.91 KDM4E (0.63) KDM4EALDH1A1HPGDHSD17B10MAPT
SCHEMBL3335014 0.89 ALDH1A1 (0.61) KDM4EALDH1A1HPGDHSD17B10MAPT
SCHEMBL3336441 0.88 KDM4E (0.59) KDM4EALDH1A1HPGDHSD17B10MAPT
SCHEMBL22956044 0.87 KDM4E (0.59) KDM4EALDH1A1HPGDHSD17B10MAPT
SCHEMBL29898236 0.86 KDM4E (1.00) KDM4EALDH1A1HPGDHSD17B10MAPT
SCHEMBL8337597 0.86 KDM4E (1.00) KDM4EALDH1A1HPGDHSD17B10MAPT
SCHEMBL1171146 0.85 ALDH1A1 (0.53) KDM4EALDH1A1HPGDHSD17B10MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1891393-A Preflux composition BAIK YANG CHEMICAL CO LTD (KR) 2007-01-10 — — CN claimed
US-20260125348-A1 ARYL HYDROCARBON RECEPTOR ACTIVATORS OREGON STATE UNIVERSITY (US) 2026-05-07 — — US disclosed
EP-4710922-A2 ARYL HYDROCARBON RECEPTOR ACTIVATORS Oregon State University (US) 2026-03-18 — — EP disclosed
EP-4003337-B1 ARYL HYDROCARBON RECEPTOR ACTIVATORS UNIV OREGON STATE (US) 2026-03-11 — — EP disclosed
US-12473262-B2 Aryl hydrocarbon receptor activators OREGON STATE UNIVERSITY (US) 2025-11-18 — — US disclosed
CN-116924995-A Method for synthesizing benzimidazole compound by catalyzing L-phenylalanine 宁夏师范学院 2023-10-24 — — CN disclosed
CN-110759903-B Novel synthesis method of thiabendazole 南开大学 2022-10-28 — — CN disclosed
US-20220281824-A1 ARYL HYDROCARBON RECEPTOR ACTIVATORS OREGON STATE UNIVERSITY (US) 2022-09-08 — — US disclosed
EP-4003337-A1 ARYL HYDROCARBON RECEPTOR ACTIVATORS Oregon State University (US) 2022-06-01 — — EP disclosed
CN-106802536-B Transfer material, method for producing same, laminate, and method for producing same 富士胶片株式会社 2022-03-04 — — CN disclosed
US-10157695-B2 — — 2018-12-18 — — US disclosed
US-10059087-B2 Transfer film, method for manufacturing transfer film, laminate, method for manufacturing laminate, capacitive input device, and image display device FUJIFILM CORPORATION (JP) 2018-08-28 — — US disclosed
CN-106802536-A Transfer materials and its manufacture method, layered product and its manufacture method 富士胶片株式会社 2017-06-06 — — CN disclosed
US-20170154704-A1 TRANSFER MATERIAL, METHOD OF MANUFACTURING TRANSFER MATERIAL, LAMINATED BODY, METHOD OF MANUFACTURING LAMINATED BODY, METHOD OF MANUFACTURING CAPACITANCE-TYPE INPUT DEVICE, AND METHOD OF MANUFACTURING IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2017-06-01 — — US disclosed
CN-106660309-A Transfer film, method for manufacturing transfer film, laminate, method for manufacturing laminate, capacitance-type input device, and image display device 富士胶片株式会社 2017-05-10 — — CN disclosed
US-20170095999-A1 TRANSFER FILM, METHOD FOR MANUFACTURING TRANSFER FILM, LAMINATE, METHOD FOR MANUFACTURING LAMINATE, CAPACITIVE INPUT DEVICE, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2017-04-06 — — US disclosed
US-8198307-B2 Imidazole derivatives having aryl piperidine substituent, method for preparation thereof and pharmaceutical compositions containing same KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2012-06-12 — — US disclosed
US-20100145054-A1 IMIDAZOLE DERIVATIVES HAVING ARYL PIPERIDINE SUBSTITUENT, METHOD FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2010-06-10 — — US disclosed
WO-2008140239-A1 IMIDAZOLE DERIVATIVES HAVING ARYL PIPERIDINE SUBSTITUENT, METHOD FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2008-11-20 — — WO disclosed
CN-1891393-A Preflux composition BAIK YANG CHEMICAL CO LTD (KR) 2007-01-10 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220281824-A1 ARYL HYDROCARBON RECEPTOR ACTIVATORS AHR, ARNT, NR0B1 KDM4E 2779/4885ALDH1A1 787/4885HPGD 917/4885
US-20260125348-A1 ARYL HYDROCARBON RECEPTOR ACTIVATORS AHR, ARNT, NR1H2 KDM4E 2619/4885ALDH1A1 2105/4885HPGD 2671/4885
US-20100145054-A1 IMIDAZOLE DERIVATIVES HAVING ARYL PIPERIDINE SUBSTITUENT, METHOD FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME TYR, MCHR1, MCHR2 KDM4E 220/4885ALDH1A1 448/4885HPGD 527/4885
US-12473262-B2 Aryl hydrocarbon receptor activators AHR, ARNT, NR0B1 KDM4E 2779/4885ALDH1A1 787/4885HPGD 917/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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