Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | PDE6D | O43924 | 1/20 | 0.63 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.63 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 5/20 | 0.59 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | DRD2 | P14416 | 2/20 | 0.54 |
| ▸ | DRD3 | P35462 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.51 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | JAK2 | O60674 | 1/20 | 0.50 |
| ▸ | JAK1 | P23458 | 1/20 | 0.50 |
| ▸ | TYK2 | P29597 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3336250 | 0.98 | ALDH1A1 (0.61) | ALDH1A1PDE6DALDH2ALDH3A1HPGD | |
| SCHEMBL11201469 | 0.95 | ALDH1A1 (0.65) | ALDH1A1PDE6DALDH2ALDH3A1HPGD | |
| SCHEMBL3331202 | 0.90 | ALDH1A1 (0.64) | ALDH1A1PDE6DALDH2ALDH3A1HPGD | |
| SCHEMBL3336215 | 0.89 | ALDH1A1 (0.63) | ALDH1A1PDE6DALDH2ALDH3A1HPGD | |
| SCHEMBL4938222 | 0.85 | HPGD (0.61) | ALDH1A1PDE6DALDH2ALDH3A1HPGD | |
| SCHEMBL4946603 | 0.84 | HPGD (0.59) | ALDH1A1PDE6DALDH2ALDH3A1HPGD | |
| SCHEMBL10323108 | 0.83 | TLR7 (0.64) | ALDH1A1PDE6DALDH2ALDH3A1HPGD | |
| SCHEMBL9321137 | 0.83 | TP53 (0.72) | ALDH1A1PDE6DALDH2ALDH3A1HPGD | |
| SCHEMBL11197015 | 0.81 | LMNA (0.67) | ALDH1A1PDE6DTP53P2RX7LMNA | |
| SCHEMBL13668139 | 0.81 | HPGD (0.57) | ALDH1A1PDE6DALDH2ALDH3A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8198307-B2 | Imidazole derivatives having aryl piperidine substituent, method for preparation thereof and pharmaceutical compositions containing same | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2012-06-12 | — | — | US | disclosed |
| US-20100145054-A1 | IMIDAZOLE DERIVATIVES HAVING ARYL PIPERIDINE SUBSTITUENT, METHOD FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2010-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100145054-A1 | IMIDAZOLE DERIVATIVES HAVING ARYL PIPERIDINE SUBSTITUENT, METHOD FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | TYR, MCHR1, MCHR2 | ALDH1A1 448/4885PDE6D 116/4885ALDH2 704/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.