Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 9/20 | 0.54 |
| ▸ | TPSD1 | Q9BZJ3 | 9/20 | 0.54 |
| ▸ | TPSG1 | Q9NRR2 | 9/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 2/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | PLAT | P00750 | 1/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.36 |
| ▸ | STAT1 | P42224 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4696461 | 1.00 | TPSAB1 (0.54) | TPSAB1TPSD1TPSG1RAB9ANPC1 | |
| SCHEMBL3335469 | 0.89 | TPSAB1 (0.68) | TPSAB1TPSD1TPSG1PLAUPRSS1 | |
| SCHEMBL3332397 | 0.89 | TPSAB1 (0.68) | TPSAB1TPSD1TPSG1PLAUPRSS1 | |
| SCHEMBL3333102 | 0.89 | TPSAB1 (0.53) | TPSAB1TPSD1TPSG1MAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7355521 | 0.80 | TPSAB1 (0.54) | TPSAB1TPSD1TPSG1LMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL7355532 | 0.80 | TPSAB1 (0.54) | TPSAB1TPSD1TPSG1LMNAALDH1A1 | |
| SCHEMBL3333866 | 0.78 | TPSAB1 (0.56) | TPSAB1TPSD1TPSG1NPC1KMT2A | |
| SCHEMBL4697341 | 0.78 | TPSAB1 (0.58) | TPSAB1TPSD1TPSG1 | |
| SCHEMBL4697345 | 0.78 | TPSAB1 (0.58) | TPSAB1TPSD1TPSG1 | |
| SCHEMBL8257538 | 0.78 | TPSAB1 (0.68) | TPSAB1TPSD1TPSG1PLAUPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100144698-A1 | SUBSTITUTED AZETIDINONES | DAIAMED (US) | 2010-06-10 | — | — | US | disclosed |
| US-20090143351-A1 | SUBSTITUTED AZETIDINONES | DAIAMED (US) | 2009-06-04 | — | — | US | disclosed |
| US-7501404-B2 | Substituted azetidinones | DAIMED (US) | 2009-03-10 | — | — | US | disclosed |
| EP-1871741-A2 | SUBSTITUTED AZETIDINONES | Daiamed, Inc. (US) | 2008-01-02 | — | — | EP | disclosed |
| US-20070105832-A1 | Substituted azetidinones | Cadrenal Therapeutics, Inc. | 2007-05-10 | — | — | US | disclosed |
| WO-2006108039-A2 | SUBSTITUTED AZETIDINONES | DAIAMED, INC. (US) | 2006-10-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070105832-A1 | Substituted azetidinones | F2R, CPA3, CFD | TPSAB1 14/4885TPSD1 24/4885TPSG1 30/4885 |
| US-20100144698-A1 | SUBSTITUTED AZETIDINONES | F2R, CPA3, CFD | TPSAB1 14/4885TPSD1 24/4885TPSG1 30/4885 |
| US-20090143351-A1 | SUBSTITUTED AZETIDINONES | F2R, CPA3, CFD | TPSAB1 14/4885TPSD1 24/4885TPSG1 30/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.