Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR55 | Q9Y2T6 | 4/20 | 0.51 |
| ▸ | ATP1A1 | P05023 | 1/20 | 0.51 |
| ▸ | ATP1B1 | P05026 | 1/20 | 0.51 |
| ▸ | ATP1A3 | P13637 | 1/20 | 0.51 |
| ▸ | ATP1B2 | P14415 | 1/20 | 0.51 |
| ▸ | ATP1A2 | P50993 | 1/20 | 0.51 |
| ▸ | ATP1B3 | P54709 | 1/20 | 0.51 |
| ▸ | FXYD2 | P54710 | 1/20 | 0.51 |
| ▸ | ATP1A4 | Q13733 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.51 |
| ▸ | HTR7 | P34969 | 7/20 | 0.51 |
| ▸ | HTR2C | P28335 | 2/20 | 0.51 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.49 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.47 |
| ▸ | IDH1 | O75874 | 4/20 | 0.46 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26614702 | 0.81 | HDAC6 (0.54) | GPR55ATP1A1ATP1B1ATP1A3ATP1B2 | |
| SCHEMBL26614705 | 0.81 | HDAC6 (0.54) | GPR55ATP1A1ATP1B1ATP1A3ATP1B2 | |
| SCHEMBL14840619 | 0.81 | GPR55 (0.58) | GPR55ATP1A1ATP1B1ATP1A3ATP1B2 | |
| SCHEMBL27850423 | 0.80 | HTR7 (0.52) | HTR7HTR2CADRA1DADRA1AADRA1B | |
| SCHEMBL5117827 | 0.78 | GPR55 (0.46) | GPR55ATP1A1ATP1B1ATP1A3ATP1B2 | |
| SCHEMBL26614624 | 0.77 | ALDH1A1 (0.53) | GPR55ATP1A1ATP1B1ATP1A3ATP1B2 | |
| SCHEMBL28794316 | 0.77 | GPR55 (0.48) | GPR55ATP1A1ATP1B1ATP1A3ATP1B2 | |
| SCHEMBL20491132 | 0.77 | HDAC6 (0.54) | GPR55ATP1A1ATP1B1ATP1A3ATP1B2 | |
| SCHEMBL18186701 | 0.76 | IDH1 (0.57) | HDAC6HTR7HTR2CADRA1DADRA1A | |
| SCHEMBL28120957 | 0.76 | HTR7 (0.57) | HTR7HTR2CADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100152219-A1 | PYRAZOLE DERIVATIVES AS INHIBITORS OF RECEPTOR TYROSINE KINASES | ASTRAZENECA R&D (SE) | 2010-06-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152219-A1 | PYRAZOLE DERIVATIVES AS INHIBITORS OF RECEPTOR TYROSINE KINASES | LTK, ERBB2, ERBB3 | GPR55 1020/4885ATP1A1 4118/4885ATP1B1 3822/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.