Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 13/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.50 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10506417 | 0.99 | LTA4H (0.65) | LTA4HL3MBTL1HRH3HRH1NPC1 | |
| SCHEMBL29986027 | 0.82 | FOXM1 (0.56) | LTA4HNPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL3336258 | 0.81 | DRD1 (0.68) | L3MBTL1HRH1 | |
| Hydrochloric Acid SCHEMBL10506424 | 0.80 | DRD1 (0.67) | L3MBTL1HRH1 | |
| SCHEMBL7138464 | 0.80 | LTA4H (1.00) | LTA4HHRH3NPC1RAB9A | |
| SCHEMBL7132003 | 0.76 | LTA4H (0.65) | LTA4HRAB9A | |
| Hydrochloric Acid SCHEMBL28062266 | 0.74 | POLB (0.51) | L3MBTL1MEN1ALDH1A1KMT2A | |
| SCHEMBL20251326 | 0.74 | L3MBTL1 (0.81) | LTA4HL3MBTL1HRH1 | |
| SCHEMBL112951 | 0.72 | HTT (0.51) | KDM4EALDH1A1 | |
| SCHEMBL9269886 | 0.71 | DRD4 (0.80) | LTA4HL3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0153160-B1 | NOVEL CYTOTOXIC AMINOALKYL PHENOL ETHERS | The University of Manitoba (CA) | 1989-05-10 | — | — | EP | claimed |
| EP-0153160-A1 | Novel cytotoxic aminoalkyl phenol ethers | The University of Manitoba (CA) | 1985-08-28 | — | — | EP | claimed |
| US-20100144660-A1 | USE OF N,N-DIETHYL-2-[-4-(PHENYLMETHYL)-PHENOXY]ETHANAMINE MONOHYDROCHLORIDE (DPPE) IN CANCER THEREAPY | YM BIOSCIENCES INC. (CA) | 2010-06-10 | — | — | US | disclosed |
| US-20040248986-A1 | Use of n,n-diethyl-2-{-4-(phenylmethyl) - phenoxy} ethanamine monohydrochloride (dppe) in cancer therapy | MANITOBA, UNIVERSITY OF (CA) | 2004-12-09 | — | — | US | disclosed |
| EP-1441710-A1 | USE OF N,N-DIETHYL-2- -4-(PHENYLMETHYL)-PHENOXY ETHANAMINE MONOHYDROCHLORIDE (DPPE) IN CANCER THERAPY | Vincent Research & Consulting, Inc. (CA) | 2004-08-04 | — | — | EP | disclosed |
| WO-2003037318-A1 | USE OF N,N-DIETHYL-2-[-4-(PHENYLMETHYL)-PHENOXY]ETHANAMINE MONOHYDROCHLORIDE (DPPE) IN CANCER THERAPY | YM BIOSCIENCES, INC. (CA) | 2003-05-08 | — | — | WO | disclosed |
| US-4803227-A | N,N-DIALKYL-2-//4-PHENYLMETHYL/PHENOXY/ETHANAMINE AND TAMOXIFE N | THE UNIVERSITY OF MANITOBA (CA) | 1989-02-07 | — | — | US | disclosed |
| EP-0153160-A1 | Novel cytotoxic aminoalkyl phenol ethers | The University of Manitoba (CA) | 1985-08-28 | — | — | EP | disclosed |