SCHEMBL333740

SCHEMBL333740

c1ccc(-c2c[nH]c(-c3ccccc3)c2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.50
AURKA O14965 1/20 0.50
THRB P10828 1/20 0.50
CASP1 P29466 1/20 0.50
TTK P33981 1/20 0.50
AURKB Q96GD4 1/20 0.50
INCENP Q9NQS7 1/20 0.50
KDM4E B2RXH2 3/20 0.46
ALDH1A1 P00352 2/20 0.46
MCL1 Q07820 2/20 0.46
HPGD P15428 1/20 0.46
GAA P10253 2/20 0.45
GFER P55789 1/20 0.45
AKT1 P31749 1/20 0.43
AKT2 P31751 1/20 0.43
CYP3A4 P08684 1/20 0.41
IDO1 P14902 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
RAB9A P51151 2/20 0.40
NPC1 O15118 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17279777 0.91 AURKA (0.47) MAPTAURKATHRBCASP1TTK
SCHEMBL17280182 0.89 AURKA (0.46) MAPTAURKATHRBCASP1TTK
SCHEMBL4400613 0.88 MMP3 (0.58) MAPTAURKATHRBCASP1TTK
SCHEMBL17279792 0.88 MAPT (0.42) MAPTAURKATHRBCASP1TTK
SCHEMBL20392618 0.88 MMP3 (0.58) MAPTAURKATHRBCASP1TTK
SCHEMBL25364857 0.88 MAPT (0.42) MAPTAURKATHRBCASP1TTK
SCHEMBL24633981 0.88 ALDH1A1 (0.58) MAPTAURKATHRBCASP1TTK
SCHEMBL11728759 0.88 KDM4E (0.42) MAPTAURKATHRBCASP1TTK
SCHEMBL17280238 0.83 CYP3A4 (0.47) MAPTAURKATHRBCASP1TTK
SCHEMBL20653569 0.83 KIF11 (0.62) MAPTALDH1A1TDP1CDK8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119100965-A Synthesis method of 2, 4-diphenyl pyrrole 南京科技职业学院 2024-12-10 CN claimed
EP-0022087-B1 STABILIZERS FOR THERMOPLASTS THAT CONTAIN CHLORINE CIBA-GEIGY AG (CH) 1983-11-23 EP claimed
US-4290940-A Pyrrole stabilizers for chlorine-containing thermoplastics CIBA-GEIGY CORPORATION (US) 1981-09-22 US claimed
WO-1981000108-A1 STABILIZERS FOR CHLORINATED THERMOPLAST CIBA GEIGY AG (CH) 1981-01-22 WO claimed
EP-0022087-A1 Stabilizers for thermoplasts that contain chlorine CIBA-GEIGY AG (CH) 1981-01-07 EP claimed
CN-112851699-B Organic compound, organic light emitting diode and device comprising the same 乐金显示有限公司 2025-02-11 CN disclosed
CN-119100965-A Synthesis method of 2, 4-diphenyl pyrrole 南京科技职业学院 2024-12-10 CN disclosed
CN-119100965-A Synthesis method of 2, 4-diphenyl pyrrole 南京科技职业学院 2024-12-10 CN disclosed
CN-119100965-A Synthesis method of 2, 4-diphenyl pyrrole 南京科技职业学院 2024-12-10 CN disclosed
WO-2024210055-A1 PHOTOELECTRIC CONVERSION MATERIAL, PHOTOELECTRIC CONVERSION ELEMENT USING SAME, OPTICAL SENSOR, DISPLAY DEVICE, AND COMPOUND 東レ株式会社 2024-10-10 WO disclosed
CN-118745196-A Method for preparing series of asymmetric aza-BODIPY dyes by quinoline fused ring pyrrole 沈阳化工大学 2024-10-08 CN disclosed
US-12065455-B2 Organic compound, organic light emitting diode and organic light emitting device including the compound LG DISPLAY CO., LTD. (KR) 2024-08-20 US disclosed
US-4758639-A Process for production of vinyl polymer SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-19 US disclosed
US-4757124-A Suspension or emulsion polymerizing vinyl chloride monomer or mixture of vinyl chloride with vinyl monomer copolymerizable therewith in reactor with walls coated with antiscaling compound containing dye or pigments SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-07-12 US disclosed
EP-0172427-A2 Process for production of vinyl chloride polymer Shin-Etsu Chemical Co., Ltd. (JP) 1986-02-26 EP disclosed
EP-0022087-B1 STABILIZERS FOR THERMOPLASTS THAT CONTAIN CHLORINE CIBA-GEIGY AG (CH) 1983-11-23 EP disclosed
US-4369276-A Pyrrole stabilizers for chlorine-containing thermoplastics CIBA-GEIGY CORPORATION (US) 1983-01-18 US disclosed
US-4290940-A Pyrrole stabilizers for chlorine-containing thermoplastics CIBA-GEIGY CORPORATION (US) 1981-09-22 US disclosed
WO-1981000108-A1 STABILIZERS FOR CHLORINATED THERMOPLAST CIBA GEIGY AG (CH) 1981-01-22 WO disclosed
EP-0022087-A1 Stabilizers for thermoplasts that contain chlorine CIBA-GEIGY AG (CH) 1981-01-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12065455-B2 Organic compound, organic light emitting diode and organic light emitting device including the compound OCIAD1, OCIAD2, OSBPL8 MAPT 520/4885AURKA 671/4885THRB 4473/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.