Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.77 |
| ▸ | MAPT | P10636 | 12/20 | 0.68 |
| ▸ | GAA | P10253 | 7/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.68 |
| ▸ | NPC1 | O15118 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.67 |
| ▸ | GFER | P55789 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 4/20 | 0.66 |
| ▸ | LMNA | P02545 | 4/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9621679 | 0.87 | RAB9A (1.00) | RAB9AMAPTGAANPC1KMT2A | |
| SCHEMBL10812081 | 0.81 | RAB9A (0.80) | RAB9AMAPTGAAALDH1A1NPC1 | |
| SCHEMBL10922446 | 0.81 | RAB9A (0.80) | RAB9AMAPTGAAALDH1A1NPC1 | |
| SCHEMBL3342093 | 0.81 | MAPT (0.72) | RAB9AMAPTGAAALDH1A1KDM4E | |
| SCHEMBL3335920 | 0.81 | MAPT (0.71) | RAB9AMAPTGAAALDH1A1KDM4E | |
| SCHEMBL13304310 | 0.81 | BAZ1A (0.64) | RAB9AMAPTGAAALDH1A1NPC1 | |
| SCHEMBL12643697 | 0.81 | MAPT (1.00) | RAB9AMAPTGAAALDH1A1NPC1 | |
| SCHEMBL10965903 | 0.80 | RAB9A (0.78) | RAB9AMAPTGAAALDH1A1NPC1 | |
| SCHEMBL10965397 | 0.80 | RAB9A (0.77) | RAB9AMAPTGAAALDH1A1NPC1 | |
| SCHEMBL3338316 | 0.79 | MAPT (0.74) | RAB9AMAPTGAAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100151064-A1 | THIAZOLHYDRAZIDES FOR TREATMENT OF NEURODEGENERATIVE DISEASES | TECHNISCHE UNIVERSITAT DARMSTADT (DE) | 2010-06-17 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100151064-A1 | THIAZOLHYDRAZIDES FOR TREATMENT OF NEURODEGENERATIVE DISEASES | HTT, MAPT, SNCA | RAB9A 2591/4885MAPT 2/4885GAA 76/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.