Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 4/20 | 0.40 |
| ▸ | TDO2 | P48775 | 2/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29437021 | 1.00 | HSD17B10 (0.46) | HSD17B10GLAEGFRALDH1A1KDM4E | |
| SCHEMBL1822381 | 0.83 | HSD17B10 (0.44) | HSD17B10GLAEGFRALDH1A1KDM4E | |
| SCHEMBL5733322 | 0.80 | GSK3B (0.48) | ALDH1A1KDM4EMAPTIDO1TDO2 | |
| SCHEMBL1820831 | 0.79 | KMT2A (0.44) | HSD17B10GLAEGFRALDH1A1KDM4E | |
| SCHEMBL32666153 | 0.77 | NQO2 (0.43) | HSD17B10ALDH1A1KDM4EMAPTMEN1 | |
| SCHEMBL5733087 | 0.77 | CREBBP (0.40) | HSD17B10ALDH1A1KDM4EMAPTALOX15 | |
| SCHEMBL6080065 | 0.76 | ALDH1A1 (0.50) | HSD17B10GLAEGFRALDH1A1KDM4E | |
| SCHEMBL29437202 | 0.76 | EGFR (0.69) | HSD17B10GLAEGFRALDH1A1KDM4E | |
| SCHEMBL1302976 | 0.76 | EGFR (0.69) | HSD17B10GLAEGFRALDH1A1KDM4E | |
| SCHEMBL7651400 | 0.75 | EGFR (0.44) | HSD17B10GLAEGFRKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240293366-A1 | TOPICAL COMPOSITIONS AND METHODS FOR TREATING INFLAMMATORY SKIN DISEASES | AZORA THERAPEUTICS, INC. | 2024-09-05 | — | — | US | disclosed |
| EP-4252844-A2 | TOPICAL COMPOSITIONS AND METHODS FOR TREATING INFLAMMATORY SKIN DISEASES | AZORA THERAPEUTICS, INC. (US) | 2023-10-04 | — | — | EP | disclosed |
| CN-114206312-A | Topical compositions and methods for treating inflammatory skin disorders | 阿佐拉治疗股份有限公司 | 2022-03-18 | — | — | CN | disclosed |
| EP-3955889-A1 | TOPICAL COMPOSITIONS AND METHODS FOR TREATING INFLAMMATORY SKIN DISEASES | AZORA THERAPEUTICS, INC. (US) | 2022-02-23 | — | — | EP | disclosed |
| US-20220023259-A1 | TOPICAL COMPOSITIONS AND METHODS FOR TREATING INFLAMMATORY SKIN DISEASES | AZORA THERAPEUTICS, INC. | 2022-01-27 | — | — | US | disclosed |
| US-11154533-B2 | Topical compositions and methods for treating inflammatory skin diseases | AZORA THERAPEUTICS, INC. (US) | 2021-10-26 | — | — | US | disclosed |
| US-20210186931-A1 | TOPICAL COMPOSITIONS AND METHODS FOR TREATING INFLAMMATORY SKIN DISEASES | AZORA THERAPEUTICS, INC. | 2021-06-24 | — | — | US | disclosed |
| US-20210139865-A1 | DEGRADATION OF SPOROPOLLENIN | NATIONAL SCIENCE FOUNDATION | 2021-05-13 | — | — | US | disclosed |
| US-10913937-B2 | Degradation of sporopollenin | LAFAYETTE COLLEGE (US) | 2021-02-09 | — | — | US | disclosed |
| WO-2020214855-A1 | TOPICAL COMPOSITIONS AND METHODS FOR TREATING INFLAMMATORY SKIN DISEASES | AZORA THERAPEUTICS, INC. (US) | 2020-10-22 | — | — | WO | disclosed |
| US-20180298351-A1 | DEGRADATION OF SPOROPOLLENIN | LAFAYETTE COLLEGE (US) | 2018-10-18 | — | — | US | disclosed |
| US-20100158842-A1 | NATURAL SKIN WHITENER: 4-HYDROXY-OXINDOLE-3-ACETIC ACID | SPECTRUM DYNAMICS LLC | 2010-06-24 | — | — | US | disclosed |
| US-20100158842-A1 | NATURAL SKIN WHITENER: 4-HYDROXY-OXINDOLE-3-ACETIC ACID | SPECTRUM DYNAMICS LLC | 2010-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210186931-A1 | TOPICAL COMPOSITIONS AND METHODS FOR TREATING INFLAMMATORY SKIN DISEASES | AHR, ARNT, TLR8 | HSD17B10 1255/4885GLA 1334/4885EGFR 505/4885 |
| US-11154533-B2 | Topical compositions and methods for treating inflammatory skin diseases | AHR, ARNT, TLR8 | HSD17B10 1255/4885GLA 1334/4885EGFR 505/4885 |
| US-20240293366-A1 | TOPICAL COMPOSITIONS AND METHODS FOR TREATING INFLAMMATORY SKIN DISEASES | AHR, ARNT, TLR8 | HSD17B10 1255/4885GLA 1334/4885EGFR 505/4885 |
| US-20220023259-A1 | TOPICAL COMPOSITIONS AND METHODS FOR TREATING INFLAMMATORY SKIN DISEASES | AHR, ARNT, TLR8 | HSD17B10 1255/4885GLA 1334/4885EGFR 505/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.