Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3339081 | 1.00 | NPC1 (0.31) | NPC1RAB9A | |
| SCHEMBL24132563 | 0.81 | NFE2L2 (0.33) | RAB9A | |
| SCHEMBL3339566 | 0.81 | MEN1 (0.33) | RAB9A | |
| SCHEMBL24495509 | 0.72 | NPC1 (0.34) | NPC1RAB9A | |
| SCHEMBL24116753 | 0.72 | — | — | |
| SCHEMBL7668274 | 0.68 | ALDH1A1 (0.44) | NPC1RAB9A | |
| SCHEMBL15878725 | 0.65 | HTR2C (0.37) | — | |
| SCHEMBL24105697 | 0.65 | HTR2C (0.35) | — | |
| SCHEMBL9431365 | 0.65 | POLB (0.35) | RAB9A | |
| SCHEMBL16067619 | 0.64 | KCNH2 (0.56) | NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8592452-B2 | Cyclic amine compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-11-26 | — | — | US | disclosed |
| US-20100152236-A1 | Cyclic amine compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-06-17 | — | — | US | disclosed |
| EP-1911743-A1 | CYCLIC AMINE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2008-04-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152236-A1 | Cyclic amine compound | AR, FSHR, NR5A1 | NPC1 2508/4885RAB9A 3173/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.