Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3339566 | 0.83 | MEN1 (0.33) | ALDH1A1MEN1KMT2ATDP1RAB9A | |
| SCHEMBL19136372 | 0.72 | ALDH1A3 (0.37) | ALDH1A1KMT2AKDM4ENPC1RAB9A | |
| SCHEMBL2794457 | 0.71 | CXCR2 (0.31) | NPC1RAB9A | |
| SCHEMBL189622 | 0.70 | ALDH1A1 (0.59) | ALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL9431365 | 0.69 | POLB (0.35) | ALDH1A1MEN1KMT2ATDP1KDM4E | |
| SCHEMBL7660116 | 0.69 | NOTUM (0.36) | NPC1RAB9A | |
| SCHEMBL3339081 | 0.68 | NPC1 (0.31) | NPC1RAB9A | |
| SCHEMBL3339084 | 0.68 | NPC1 (0.31) | NPC1RAB9A | |
| SCHEMBL7656482 | 0.67 | NPC1 (0.31) | NPC1RAB9A | |
| SCHEMBL30600426 | 0.67 | ALDH1A1 (0.68) | ALDH1A1MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6344462-B1 | Heterocyclic compounds as bradykinin antagonists | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-02-05 | — | — | US | disclosed |
| US-6100284-A | ANTIALLERGENS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-08-08 | — | — | US | disclosed |
| US-6008229-A | TREATING ALLERGY, INFLAMMATION, AUTOIMMUNE DISEASE, SHOCK, PAIN | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-12-28 | — | — | US | disclosed |
| EP-0861243-A1 | HETEROCYCLIC COMPOUNDS AS BRADYKININ ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-09-02 | — | — | EP | disclosed |
| WO-1997011069-A1 | HETEROCYCLIC COMPOUNDS AS BRADYKININ ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-03-27 | — | — | WO | disclosed |