Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 2/20 | 0.44 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 4/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 4/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CCR3 | P51677 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12607837 | 0.91 | MCHR1 (0.45) | MCHR1MAP4K1PRMT5WDR77HCRTR1 | |
| Trifluoroacetic Acid SCHEMBL3042254 | 0.81 | MAP4K1 (0.42) | MCHR1MAP4K1ADRA1A | |
| SCHEMBL3339830 | 0.79 | MCHR1 (0.42) | MCHR1MAP4K1DPP4DPP7PRMT5 | |
| SCHEMBL1786382 | 0.76 | MAP4K1 (0.44) | MAP4K1DPP4PRMT5WDR77DPP8 | |
| Trifluoroacetic Acid SCHEMBL3342708 | 0.76 | PARP1 (0.36) | MAP4K1HRH3USP30 | |
| Trifluoroacetic Acid SCHEMBL3339970 | 0.76 | PARP1 (0.36) | MAP4K1 | |
| Hydrochloric Acid SCHEMBL3340501 | 0.76 | MAP4K1 (0.44) | MAP4K1DPP4PRMT5WDR77DPP8 | |
| Trifluoroacetic Acid SCHEMBL3343257 | 0.75 | MAP4K1 (0.46) | MCHR1MAP4K1DPP4DPP7DPP9 | |
| Trifluoroacetic Acid SCHEMBL3340019 | 0.74 | SLC2A1 (0.41) | DPP4DPP7HCRTR1CCR3 | |
| Trifluoroacetic Acid SCHEMBL3339550 | 0.74 | DPP4 (0.42) | MAP4K1DPP4DPP7PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140323487-A1 | Novel Compounds As Antagonists Or Inverse Agonists At Opioid Receptors | GLAXOSMITHKLINE LLC | 2014-10-30 | — | — | US | disclosed |
| US-20100113512-A1 | METHOD OF TREATMENT USING NOVEL ANTAGONISTS OR INVERSE AGONISTS AT OPIOID RECEPTORS | IGNAR DIANE MICHELE | 2010-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100113512-A1 | METHOD OF TREATMENT USING NOVEL ANTAGONISTS OR INVERSE AGONISTS AT OPIOID RECEPTORS | OPRL1, OPRD1, OPRK1 | MCHR1 133/4885MAP4K1 2850/4885DPP4 1431/4885 |
| US-20140323487-A1 | Novel Compounds As Antagonists Or Inverse Agonists At Opioid Receptors | OPRL1, OPRM1, OPRK1 | MCHR1 83/4885MAP4K1 1472/4885DPP4 1228/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.