SCHEMBL3340346

SCHEMBL3340346

CCO[Si](OCC)(OCC)OCc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.46
IDO1 P14902 1/20 0.43
TP53 P04637 1/20 0.42
AGXT P21549 1/20 0.41
ALDH1A1 P00352 3/20 0.41
MAOB P27338 1/20 0.40
L3MBTL1 Q9Y468 3/20 0.39
MAPT P10636 1/20 0.39
MAPK1 P28482 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
AOC3 Q16853 1/20 0.39
HTR1A P08908 1/20 0.39
ADRA1D P25100 1/20 0.39
ADRA1A P35348 1/20 0.39
ADRA1B P35368 1/20 0.39
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA9 Q16790 1/20 0.36
LMNA P02545 1/20 0.36
CYP1A2 P05177 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3343520 1.00 TSHR (0.46) TSHRIDO1TP53AGXTALDH1A1
SCHEMBL10568255 1.00 TSHR (0.46) TSHRIDO1TP53AGXTALDH1A1
SCHEMBL30338391 0.90 TSHR (0.41) TSHRIDO1TP53AGXTALDH1A1
SCHEMBL766418 0.89 TSHR (0.57) TSHRIDO1AGXTALDH1A1MAOB
SCHEMBL28407636 0.88 MAOB (0.37) TSHRIDO1TP53AGXTALDH1A1
SCHEMBL19809178 0.86 CETP (0.41) TSHRTP53ALDH1A1L3MBTL1MAPK1
SCHEMBL11278778 0.83 HTR1A (0.36) TSHRALDH1A1MAOBL3MBTL1MAPT
SCHEMBL18297947 0.82 TSHR (0.41) TSHRIDO1TP53AGXTALDH1A1
SCHEMBL18297909 0.82 TSHR (0.41) TSHRIDO1TP53AGXTALDH1A1
SCHEMBL28165546 0.82 TSHR (0.41) TSHRIDO1TP53AGXTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119608184-A Ball-milling catalytic hydrosilylation reaction method and catalyst used in same 浙江大学 2025-03-14 CN disclosed
US-11912731-B2 Use of silylated formiates as hydrosilane equivalents COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2024-02-27 US disclosed
EP-3103805-B1 SILANOL COMPOUND, COMPOSITION, AND METHOD FOR PRODUCING SILANOL COMPOUND AIST (JP) 2020-11-18 EP disclosed
CN-106632744-B Propylene polymerization catalyst, preparation method and application 北京化工大学 2020-05-15 CN disclosed
US-10308670-B2 Silanol compound, composition, and method for producing silanol compound NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2019-06-04 US disclosed
CN-108484805-A A kind of Highh activity polyethylene Ziegler-Natta catalyst and its preparation method and application 营口风光新材料股份有限公司 2018-09-04 CN disclosed
US-20170183363-A1 Silanol Compound, Composition, and Method for Producing Silanol Compound NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2017-06-29 US disclosed
EP-3103805-A1 SILANOL COMPOUND, COMPOSITION, AND METHOD FOR PRODUCING SILANOL COMPOUND National Institute of Advanced Industrial Science and Technology (JP) 2016-12-14 EP disclosed
CN-102348765-B Oil-in-water silicone emulsion composition DOW CORNING TORAY CO.,LTD. (JP) 2015-09-09 CN disclosed
US-8968458-B2 Composition for resist underlayer film and process for producing same JSR CORPORATION (JP) 2015-03-03 US disclosed
CN-102348765-A Oil-in-water silicone emulsion composition DOW CORNING TORAY CO LTD 2012-02-08 CN disclosed
CN-102348764-A Oil-in-water silicone emulsion composition DOW CORNING TORAY CO LTD 2012-02-08 CN disclosed
US-20100151384-A1 COMPOSITION FOR RESIST UNDERLAYER FILM AND PROCESS FOR PRODUCING SAME JSR CORPORATION (JP) 2010-06-17 US disclosed
US-20090050020-A1 COMPOSITION FOR RESIST UNDERLAYER FILM AND PROCESS FOR PRODUCING SAME JSR CORPORATION (JP) 2009-02-26 US disclosed
CN-101133364-A Composition for resist underlayer film and method for producing same JSR CORP (JP) 2008-02-27 CN disclosed
EP-1855159-A1 COMPOSITION FOR UNDERLAYER FILM OF RESIST AND PROCESS FOR PRODUCING THE SAME JSR Corporation (JP) 2007-11-14 EP disclosed
EP-0754739-B1 Curable coating composition KANSAI PAINT CO LTD (JP) 2003-10-29 EP disclosed
US-5684095-A POLYESTER, POLYEPOXIDE, SILICON COMPOUND AND CHELATE CMPOUND IN SOLVENT KANSAI PAINT COMPANY, LIMITED (JP) 1997-11-04 US disclosed
EP-0754739-A2 Curable coating composition KANSAI PAINT CO., LTD. (JP) 1997-01-22 EP disclosed
US-4732929-A Silicon-containing polyols PPG INDUSTRIES, INC. (US) 1988-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11912731-B2 Use of silylated formiates as hydrosilane equivalents PFAS, EPM2A, CYP2F1 TSHR 3111/4885IDO1 4355/4885TP53 2737/4885
US-20170183363-A1 Silanol Compound, Composition, and Method for Producing Silanol Compound LSS, MSMO1, ALG3 TSHR 4865/4885IDO1 3463/4885TP53 2082/4885
US-10308670-B2 Silanol compound, composition, and method for producing silanol compound LSS, MSMO1, ALG3 TSHR 4865/4885IDO1 3463/4885TP53 2082/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.