Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.48 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3571632 | 0.82 | HTR6 (0.63) | PKMNR3C2POLBGAAHTR6 | |
| SCHEMBL3339338 | 0.81 | PKM (0.49) | PKMNR3C2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL3340161 | 0.77 | HTR6 (0.57) | PKMNR3C2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL3343842 | 0.74 | LMNA (0.43) | PKMNR3C2CYP2D6POLBGAA | |
| SCHEMBL3336857 | 0.74 | HTR6 (0.48) | PKMNR3C2POLBGAAHTR6 | |
| SCHEMBL3343504 | 0.74 | HTR6 (0.48) | PKMNR3C2POLBGAAHTR6 | |
| SCHEMBL3337638 | 0.70 | HTR6 (0.57) | NR3C2CYP3A4CYP2D6CYP2C9HTR6 | |
| SCHEMBL8208940 | 0.69 | HTR6 (0.46) | PKMHTR6SMN1; SMN2 | |
| SCHEMBL3334308 | 0.68 | LMNA (0.42) | PKMNR3C2POLBGAAHTR6 | |
| SCHEMBL3341196 | 0.68 | HTR6 (0.48) | PKMNR3C2POLBGAAHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100152177-A1 | COMPOUNDS HAVING 5-HT6 RECEPTOR AFFINITY | MEMORY PHARMACEUTICALS CORPORATION (US) | 2010-06-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152177-A1 | COMPOUNDS HAVING 5-HT6 RECEPTOR AFFINITY | HTR6, HTR3B, HTR1B | PKM 3353/4885NR3C2 593/4885CYP3A4 567/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.