Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 9/20 | 0.69 |
| ▸ | PPARD | Q03181 | 9/20 | 0.69 |
| ▸ | PPARA | Q07869 | 9/20 | 0.69 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.69 |
| ▸ | FABP4 | P15090 | 4/20 | 0.69 |
| ▸ | TERT | O14746 | 3/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.69 |
| ▸ | MAPT | P10636 | 2/20 | 0.69 |
| ▸ | BLM | P54132 | 2/20 | 0.69 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.69 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | GMNN | O75496 | 1/20 | 0.69 |
| ▸ | USP2 | O75604 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.69 |
| ▸ | POLB | P06746 | 1/20 | 0.69 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.69 |
| ▸ | APEX1 | P27695 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9128942 | 1.00 | PPARG (0.69) | PPARGPPARDPPARAPTPN1FABP4 | |
| SCHEMBL28183464 | 1.00 | PPARG (0.69) | PPARGPPARDPPARAPTPN1FABP4 | |
| SCHEMBL8149939 | 1.00 | PPARG (0.69) | PPARGPPARDPPARAPTPN1FABP4 | |
| SCHEMBL27779756 | 1.00 | PPARG (0.69) | PPARGPPARDPPARAPTPN1FABP4 | |
| SCHEMBL29724318 | 1.00 | PPARG (0.69) | PPARGPPARDPPARAPTPN1FABP4 | |
| SCHEMBL1665622 | 0.96 | TOP1 (0.67) | PPARGPPARDPPARAPTPN1FABP4 | |
| SCHEMBL11410056 | 0.96 | F7 (0.69) | PPARGPPARDPPARAPTPN1FABP4 | |
| SCHEMBL18185533 | 0.87 | PPARG (0.77) | PPARGPPARDPPARAPTPN1FABP4 | |
| SCHEMBL17540721 | 0.85 | TERT (0.48) | PPARGPPARDPPARAPTPN1FABP4 | |
| SCHEMBL28849304 | 0.85 | TERT (0.48) | PPARGPPARDPPARAPTPN1FABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170210775-A1 | GUGGULPHOSPHOLIPID METHODS AND COMPOSITIONS | JINA PHARMACEUTICALS, INC. | 2017-07-27 | — | — | US | disclosed |
| US-9637515-B2 | Guggulphospholipid methods and compositions | JINA PHARMACEUTICALS, INC. (US) | 2017-05-02 | — | — | US | disclosed |
| EP-2088865-B1 | GUGGULPHOSPHOLIPID METHODS AND COMPOSITIONS | JINA PHARMACEUTICALS INC (US) | 2015-10-21 | — | — | EP | disclosed |
| US-20100151002-A1 | Guggulphospholipid Methods and Compositions | JINA PHARMACEUTICALS, INC. (US) | 2010-06-17 | — | — | US | disclosed |
| US-20050154059-A1 | Method of treating type III hypersensitive reaction-related diseases and conditions by using conjugated linoleic acid | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2005-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100151002-A1 | Guggulphospholipid Methods and Compositions | SGMS2, SGMS1, PLA2G5 | PPARG 64/4885PPARD 305/4885PPARA 265/4885 |
| US-20170210775-A1 | GUGGULPHOSPHOLIPID METHODS AND COMPOSITIONS | SGMS1, SGMS2, GGPS1 | PPARG 48/4885PPARD 305/4885PPARA 264/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.