Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 7/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.45 |
| ▸ | TOP2A | P11388 | 1/20 | 0.45 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3341252 | 0.82 | KDM4E (0.58) | HPGDHSD17B10KDM4EALDH1A1LMNA | |
| Cyclopropane SCHEMBL3447310 | 0.81 | ALDH1A1 (0.56) | HPGDHSD17B10KDM4EALDH1A1LMNA | |
| SCHEMBL13576341 | 0.77 | KDM4E (0.42) | HPGDHSD17B10KDM4EALDH1A1LMNA | |
| SCHEMBL5303665 | 0.77 | KDM4E (0.48) | HPGDHSD17B10KDM4EALDH1A1CYP1A2 | |
| SCHEMBL7511784 | 0.77 | KDM4E (0.48) | HPGDHSD17B10KDM4EALDH1A1LMNA | |
| SCHEMBL9443458 | 0.75 | HPGD (0.52) | HPGDHSD17B10KDM4EALDH1A1LMNA | |
| SCHEMBL4962381 | 0.74 | KDM4E (0.48) | HPGDHSD17B10KDM4EALDH1A1LMNA | |
| SCHEMBL1421967 | 0.74 | KDM4E (0.55) | HPGDHSD17B10KDM4EALDH1A1CYP1A2 | |
| SCHEMBL7557789 | 0.73 | ALDH1A1 (0.50) | HPGDHSD17B10KDM4EALDH1A1LMNA | |
| SCHEMBL631845 | 0.72 | KDM4E (0.52) | HPGDHSD17B10KDM4EALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1453846-A1 | MACROLIDES | GLAXO GROUP LIMITED (GB) | 2004-09-08 | — | — | EP | disclosed |
| WO-2003042228-A1 | MACROLIDES | GLAXO GROUP LIMITED (GB) | 2003-05-22 | — | — | WO | disclosed |