⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7288916 | 0.82 | — | — | |
| SCHEMBL10243314 | 0.82 | — | — | |
| SCHEMBL7288913 | 0.82 | — | — | |
| SCHEMBL20089272 | 0.78 | — | — | |
| SCHEMBL325397 | 0.77 | — | — | |
| SCHEMBL9510313 | 0.75 | — | — | |
| SCHEMBL4380206 | 0.73 | — | — | |
| SCHEMBL325942 | 0.73 | — | — | |
| SCHEMBL2169769 | 0.73 | — | — | |
| SCHEMBL2169763 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1313851-A | Preparation method of vitamin A | AGREVO ANIMAL NUTRITION S A (FR) | 2001-09-19 | — | — | CN | claimed |
| US-7723536-B2 | Synthetic techniques and intermediates for polyhydroxy dienyl lactones and mimics thereof | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2010-05-25 | — | — | US | disclosed |
| US-7700783-B2 | Synthesis of discodermolide and variants thereof | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2010-04-20 | — | — | US | disclosed |
| US-7652031-B2 | Compounds which mimic the chemical and biological properties of discodermolide | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2010-01-26 | — | — | US | disclosed |
| US-20090187031-A1 | Synthetic techniques and intermediates for polyhydroxy dienyl lactones and mimics thereof | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2009-07-23 | — | — | US | disclosed |
| CN-101389619-A | Synthetic techniques and intermediates for polyhydroxy dienyl lactones and mimics thereof | UNIV PENNSYLVANIA (US) | 2009-03-18 | — | — | CN | disclosed |
| US-7368585-B2 | Synthetic techniques and intermediates for polyhydroxy dienyl lactones and mimics thereof | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2008-05-06 | — | — | US | disclosed |
| US-20070276144-A1 | Synthesis Of Discodermolide And Variants Thereof | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | 2007-11-29 | — | — | US | disclosed |
| US-20070043223-A1 | Synthetic techniques and intermediates for polyhydroxy dienyl lactones and mimics thereof | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-02-22 | — | — | US | disclosed |
| EP-1585725-A4 | COMPOUNDS WHICH MIMIC THE CHEMICAL AND BIOLOGICAL PROPERTIES OF DISCODERMOLIDE | UNIV PENNSYLVANIA (US) | 2006-06-07 | — | — | EP | disclosed |
| US-20020103387-A1 | Compounds which mimic the chemical and biological properties of discodermolide | NIH - DEITR | 2002-08-01 | — | — | US | disclosed |
| EP-1105383-A4 | SYNTHETIC TECHNIQUES AND INTERMEDIATES FOR POLYHYDROXY, DIENYL LACTONE DERIVATIVES | UNIV PENNSYLVANIA (US) | 2002-06-26 | — | — | EP | disclosed |
| WO-2002046150-A2 | COMPOUNDS WHICH MIMIC THE CHEMICAL AND BIOLOGICAL PROPERTIES OF DISCODERMOLIDE | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA CENTER FOR TECHNOLOGY TRANSFER (US) | 2002-06-13 | — | — | WO | disclosed |
| WO-2001042179-A9 | COMPOUNDS WHICH MIMIC THE CHEMICAL AND BIOLOGICAL PROPERTIES OF DISCODERMOLIDE | UNIV PENNSYLVANIA (US) | 2002-05-23 | — | — | WO | disclosed |
| US-20020052028-A1 | Bio-intermediates for use in the chemical synthesis of polyketides | KOSAN BIOSCIENCES, INC. | 2002-05-02 | — | — | US | disclosed |
| WO-2002012534-A2 | BIO-INTERMEDIATES FOR USE IN THE CHEMICAL SYNTHESIS OF POLYKETIDES | KOSAN BIOSCIENCES, INC. (US) | 2002-02-14 | — | — | WO | disclosed |
| EP-1105383-A2 | SYNTHETIC TECHNIQUES AND INTERMEDIATES FOR POLYHYDROXY, DIENYL LACTONE DERIVATIVES | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2001-06-13 | — | — | EP | disclosed |
| US-6242616-B1 | FORMED BY ALKYLATION, ALKENYLATION, BLOCKING, AND DEBLOCKING;USED AS IMMUNOSUPPRESANTS AND ANTITUMOR AGENTS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | 2001-06-05 | — | — | US | disclosed |
| US-6096904-A | Synthetic techniques and intermediates for polyhydroxy, dienyl lactone derivatives | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2000-08-01 | — | — | US | disclosed |
| WO-2000004865-A2 | SYNTHETIC TECHNIQUES AND INTERMEDIATES FOR POLYHYDROXY, DIENYL LACTONE DERIVATIVES | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2000-02-03 | — | — | WO | disclosed |