SCHEMBL3342299

SCHEMBL3342299

CC(C)(C)[Si](C)(C)OCCN(CCO[Si](C)(C)C(C)(C)C)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
KMT2A Q03164 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
NCF1 P14598 1/20 0.38
DUT P33316 2/20 0.35
TSHR P16473 1/20 0.34
TAAR1 Q96RJ0 3/20 0.33
CYP2D6 P10635 1/20 0.33
NTSR1 P30989 1/20 0.32
EGFR P00533 1/20 0.32
ERBB2 P04626 1/20 0.32
DGAT1 O75907 1/20 0.32
CHRM2 P08172 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4652904 0.83 BACE1 (0.36) CYP3A4DUTTSHRNTSR1DGAT1
SCHEMBL13302934 0.83 DUT (0.34) DUTDGAT1
SCHEMBL7717528 0.83 DUT (0.37) DUTTAAR1DGAT1
SCHEMBL4465723 0.83 ALDH1A1 (0.43) CYP3A4NCF1DUTTSHRDGAT1
SCHEMBL4654972 0.83 NOX1 (0.45) CYP2C19SMN1; SMN2EGFR
SCHEMBL6933156 0.82 DUT (0.33) DUTDGAT1
SCHEMBL3019402 0.82 MTNR1A (0.34) KMT2ADUTTSHRTAAR1EGFR
SCHEMBL98656 0.80 ALDH1A1 (0.34) DUT
SCHEMBL1234774 0.80 ALDH1A1 (0.49) MEN1KMT2ASMN1; SMN2DUTDGAT1
SCHEMBL13302932 0.80 DUT (0.32) DUTDGAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8197722-B2 Irradiating the compound (containing two electron donor groups and a bridge of pi-conjugated bonds containing electron donor groups) with light, and the compound is converted to a multi-photon electronically excited state THE CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2012-06-12 US disclosed
US-8197722-B2 Irradiating the compound (containing two electron donor groups and a bridge of pi-conjugated bonds containing electron donor groups) with light, and the compound is converted to a multi-photon electronically excited state THE CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2012-06-12 US disclosed
US-20100152338-A1 NONLINEAR OPTICAL MATERIAL COMPOSITION AND METHOD OF MANUFACTURE NITTO DENKO CORPORATION (JP) 2010-06-17 US disclosed
US-20100152338-A1 NONLINEAR OPTICAL MATERIAL COMPOSITION AND METHOD OF MANUFACTURE NITTO DENKO CORPORATION (JP) 2010-06-17 US disclosed
WO-2008109701-A1 NONLINEAR OPTICAL MATERIAL COMPOSITION AND METHOD OF MANUFACTURE NITTO DENKO CORPORATION (JP) 2008-09-12 WO disclosed
EP-0747704-B1 Immunoassay element containing a diaryl telluride compound to increase its stability ORTHO CLINICAL DIAGNOSTICS INC (US) 2003-12-10 EP disclosed
EP-0903583-B1 Reduction in first slide bias and improved enzyme stability by incorporation of diaryl tellurides in the gravure layer of dry-film immunoassay elements ORTHO CLINICAL DIAGNOSTICS INC (US) 2003-11-12 EP disclosed
US-20020185634-A1 Two-photon or higher-order absorbing optical materials and methods of use CALIFORNIA INSTITUTE OF TECHNOLOGY 2002-12-12 US disclosed
US-6267913-B1 IN HOLOGRAPHYL, BIOLOGY, OPTICAL DATA STORAGE CALIFORNIA INSTITUTE OF TECHNOLOGY 2001-07-31 US disclosed
WO-1998021521-A9 TWO-PHOTON OR HIGHER-ORDER ABSORBING OPTICAL MATERIALS AND METHODS OF USE CALIFORNIA INST OF TECHN (US) 2000-03-02 WO disclosed
EP-0903583-A2 Reduction in first slide bias and improved enzyme stability by incorporation of diaryl tellurides in the gravure layer of dry-film immunoassay elements Ortho-Clinical Diagnostics, Inc. (US) 1999-03-24 EP disclosed
WO-1998021521-A1 TWO-PHOTON OR HIGHER-ORDER ABSORBING OPTICAL MATERIALS AND METHODS OF USE CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1998-05-22 WO disclosed
EP-0747704-A2 Immunoassay element containing a diaryl telluride compound to increase its stability Johnson & Johnson Clinical Diagnostics, Inc. (US) 1996-12-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100152338-A1 NONLINEAR OPTICAL MATERIAL COMPOSITION AND METHOD OF MANUFACTURE C5, OR10J3, C1S MEN1 4278/4885CYP3A4 1649/4885CYP2C9 1996/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.