Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3235007 | 0.74 | KDM4E (0.33) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL5494922 | 0.74 | KDM4E (0.33) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL22115886 | 0.74 | KDM4E (0.33) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL1491181 | 0.74 | KDM4E (0.33) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL1661412 | 0.74 | BRD4 (0.34) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL10592009 | 0.74 | KDM4E (0.34) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL2638049 | 0.74 | KDM4E (0.34) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL5999468 | 0.71 | LMNA (0.42) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL15201897 | 0.71 | HTR2C (0.32) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL23346752 | 0.69 | HTR2C (0.31) | KDM4EMEN1ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118109945-A | High-strength flame-retardant elastic fabric and preparation method thereof | 合肥楚欣纺织有限公司 | 2024-05-31 | — | — | CN | claimed |
| CN-105164131-A | Tricyclic heterocycles as bet protein inhibitors | INCYTE CORP | 2015-12-16 | — | — | CN | claimed |
| US-6679923-B2 | HAIR DYEING FORMULATION CONTAINING PYRAZOLIN-4,5-DIONES AND AT LEAST ONE AROMATIC PRIMARY AMINE ENABLES THE DYEING OF KERATIN FIBERS WITHOUT AND OXIDIZING AGENT IN SHADES WHICH ARE STRONG, VARIED, RESISTANT AND LESS SELECTIVE | L'OREAL S.A. (FR) | 2004-01-20 | — | — | US | claimed |
| US-20020194685-A1 | Composition for dyeing keratin fibres, comprising a pyrazoline-4, 5-dione and an aromatic primary amine | L'OREAL S.A. (FR) | 2002-12-26 | — | — | US | claimed |
| US-6464732-B2 | HAIR DYE MIXTURE | L'OREAL S.A. (FR) | 2002-10-15 | — | — | US | claimed |
| US-20020040508-A1 | COMPOSITION FOR DYEING KERATIN FIBRES,COMPRISING A PYRAZOLIN-4,5-DIONE AND AN AROMATIC PRIMARY AMINE | L'OREAL S.A. (FR) | 2002-04-11 | — | — | US | claimed |
| EP-1144408-A1 | SUBSTITUTED 1-(PIERIDIN-4-YL)-3-(ARYL) ISOTHIOUREAS THEIR PREPARATION AND THERAPEUTIC APPLICATION | PIERRE FABRE MEDICAMENT (FR) | 2001-10-17 | — | — | EP | claimed |
| WO-2000043391-A1 | SUBSTITUTED 1-(PIERIDIN-4-YL)-3-(ARYL) ISOTHIOUREAS THEIR PREPARATION AND THERAPEUTIC APPLICATION | PIERRE FABRE MEDICAMENT (FR) | 2000-07-27 | — | — | WO | claimed |
| EP-0981320-A1 | COMPOSITION FOR DYEING KERATIN FIBRES COMPRISING A PYRAZOLIN-4,5-DIONE AND AN AROMATIC PRIMARY AMINE | L'OREAL (FR) | 2000-03-01 | — | — | EP | claimed |
| WO-1998051268-A1 | COMPOSITION FOR DYEING KERATIN FIBRES COMPRISING A PYRAZOLIN-4,5-DIONE AND AN AROMATIC PRIMARY AMINE | L'OREAL (FR) | 1998-11-19 | — | — | WO | claimed |
| EP-0103797-B1 | SUBSTITUTED BENZOXAZINE DERIVATIVES | BAYER AG (DE) | 1986-11-26 | — | — | EP | claimed |
| JP-61030586-A | — | — | None | — | — | JP | disclosed |
| JP-1034982-A | — | — | None | — | — | JP | disclosed |
| JP-61140573-A | — | — | None | — | — | JP | disclosed |
| US-12433896-B2 | Deuterated analogs of etifoxine, their derivatives and uses thereof | GABA THERAPEUTICS INC. (US) | 2025-10-07 | — | — | US | disclosed |
| JP-S61140573-A | AMINOBENZOXAZINE DERIVATIVE AND PREPARATION THEREOF | SUMITOMO CHEM CO LTD | 1986-06-27 | — | — | JP | disclosed |
| EP-0176101-A1 | Triazolopyridazines, and their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1986-04-02 | — | — | EP | disclosed |
| JP-S6130586-A | TETRAHYDROPHTHALIMIDE DERIVATIVE, ITS PREPARATION, AND HERBICIDE COMPRISING IT AS ACTIVE INGREDIENT | SUMITOMO CHEM CO LTD | 1986-02-12 | — | — | JP | disclosed |
| US-4537888-A | Substituted benzoxazine derivatives and fungicidal use | BAYER AKTIENGESELLSCHAFT (DE) | 1985-08-27 | — | — | US | disclosed |
| JP-S06130586-A | — | — | 0001-01-01 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12433896-B2 | Deuterated analogs of etifoxine, their derivatives and uses thereof | CYP2F1, CYP3A5, CYP4F3 | KDM4E 1625/4885MEN1 985/4885ALDH1A1 1324/4885 |
| US-20020194685-A1 | Composition for dyeing keratin fibres, comprising a pyrazoline-4, 5-dione and an aromatic primary amine | KRT18, KLK5, MARK1 | KDM4E 376/4885MEN1 3401/4885ALDH1A1 185/4885 |
| US-20020040508-A1 | COMPOSITION FOR DYEING KERATIN FIBRES,COMPRISING A PYRAZOLIN-4,5-DIONE AND AN AROMATIC PRIMARY AMINE | KRT18, KLK5, H1-5 | KDM4E 292/4885MEN1 3896/4885ALDH1A1 326/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.