SCHEMBL23346752

SCHEMBL23346752

CC(C)(C)N1C=Cc2ccccc2O1

nearest known ligand 0.31

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 1/20 0.31
HTR2B P41595 1/20 0.31
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24916174 0.82
SCHEMBL1661412 0.74 BRD4 (0.34) HTR2CHTR2BKDM4EMEN1ALDH1A1
SCHEMBL22115886 0.69 KDM4E (0.33) HTR2CHTR2BKDM4EMEN1ALDH1A1
SCHEMBL5494922 0.69 KDM4E (0.33) HTR2CHTR2BKDM4EMEN1ALDH1A1
SCHEMBL3342528 0.69 KDM4E (0.37) HTR2CHTR2BKDM4EMEN1ALDH1A1
SCHEMBL1491181 0.69 KDM4E (0.33) HTR2CHTR2BKDM4EMEN1ALDH1A1
SCHEMBL3235007 0.69 KDM4E (0.33) HTR2CHTR2BKDM4EMEN1ALDH1A1
SCHEMBL15201897 0.67 HTR2C (0.32) HTR2CHTR2BKDM4EMEN1ALDH1A1
SCHEMBL6256159 0.66
SCHEMBL7383136 0.65 HTR2C (0.31) HTR2CHTR2BKDM4EMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230399355-A1 ANTIMICROBIAL COMPOUNDS, COMPOSITIONS, AND USES THEREOF Lakewood Amedex, Inc. 2023-12-14 US disclosed
US-20230399355-A1 ANTIMICROBIAL COMPOUNDS, COMPOSITIONS, AND USES THEREOF Lakewood Amedex, Inc. 2023-12-14 US disclosed
US-11795192-B2 Antimicrobial compounds, compositions, and uses thereof Lakewood Amedex, Inc. (US) 2023-10-24 US disclosed
US-11795192-B2 Antimicrobial compounds, compositions, and uses thereof Lakewood Amedex, Inc. (US) 2023-10-24 US disclosed
US-20230026056-A1 ANTIMICROBIAL COMPOUNDS, COMPOSITIONS, AND USES THEREOF Lakewood Amedex, Inc. 2023-01-26 US disclosed
US-20210139522-A1 ANTIMICROBIAL COMPOUNDS, COMPOSITIONS, AND USES THEREOF Lakewood Amedex, Inc. 2021-05-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210139522-A1 ANTIMICROBIAL COMPOUNDS, COMPOSITIONS, AND USES THEREOF CFTR, ABCB11, CEL HTR2C 4741/4885HTR2B 4768/4885KDM4E 4745/4885
US-20230026056-A1 ANTIMICROBIAL COMPOUNDS, COMPOSITIONS, AND USES THEREOF CAT, MPO, NISCH HTR2C 4820/4885HTR2B 4681/4885KDM4E 4759/4885
US-11795192-B2 Antimicrobial compounds, compositions, and uses thereof CAT, MPO, NISCH HTR2C 4820/4885HTR2B 4681/4885KDM4E 4759/4885
US-20230399355-A1 ANTIMICROBIAL COMPOUNDS, COMPOSITIONS, AND USES THEREOF CAT, MPO, NISCH HTR2C 4820/4885HTR2B 4681/4885KDM4E 4759/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.