Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | CCL2 | P13500 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | UBE2N | P61088 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15201897 | 0.75 | HTR2C (0.32) | MEN1MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL22115886 | 0.74 | KDM4E (0.33) | MEN1MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL5494922 | 0.74 | KDM4E (0.33) | MEN1MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL3342528 | 0.74 | KDM4E (0.37) | MEN1MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL3235007 | 0.74 | KDM4E (0.33) | MEN1MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL1491181 | 0.74 | KDM4E (0.33) | MEN1MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL23346752 | 0.74 | HTR2C (0.31) | MEN1MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL23346683 | 0.72 | CA12 (0.42) | MEN1MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL23346689 | 0.72 | KDM4E (0.44) | MEN1MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL253209 | 0.71 | ALDH1A1 (0.39) | MEN1MAPTKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4282358-A | CYCLIZATION OF 2-HALOPHENOXYANILINES | CIBA-GEIGY CORPORATION (US) | 1981-08-04 | — | — | US | claimed |
| CN-115611821-B | Low-dielectric and high-heat-resistance aza calixarene resin, and preparation method and application thereof | 山东大学 | 2024-03-26 | — | — | CN | disclosed |
| EP-4272832-A2 | ANTIMICROBIAL COMPOUNDS, COMPOSITIONS, AND USES THEREOF | Lakewood Amedex, Inc. (US) | 2023-11-08 | — | — | EP | disclosed |
| CN-115611821-A | Low dielectric and high heat-resistant azacalixarene resin and preparation method and application thereof | 山东大学 | 2023-01-17 | — | — | CN | disclosed |
| US-9249087-B2 | HDAC inhibitors and therapeutic methods using the same | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2016-02-02 | — | — | US | disclosed |
| US-20140128408-A1 | HDAC INHIBITORS AND THERAPEUTIC METHODS USING THE SAME | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2014-05-08 | — | — | US | disclosed |
| EP-2314579-A1 | Fast-curing benzoxazine compounds | Henkel AG & Co. KGaA (DE) | 2011-04-27 | — | — | EP | disclosed |
| US-7112584-B2 | Nonsteroidal antiinflammatory agents | SCHERING AG (DE) | 2006-09-26 | — | — | US | disclosed |
| EP-1182238-B1 | Ink jet printing method | EASTMAN KODAK CO (US) | 2005-01-05 | — | — | EP | disclosed |
| US-20040209875-A1 | Nonsteroidal antiinflammatory agents | SCHERIN AKTIENGESELLSCHAFT (DE) | 2004-10-21 | — | — | US | disclosed |
| US-6419354-B1 | PRINTING IN RESPONSE TO DIGITAL SIGNALS | EASTMAN KODAK COMPANY | 2002-07-16 | — | — | US | disclosed |
| EP-1182240-A2 | Ink jet ink composition | EASTMAN KODAK COMPANY (US) | 2002-02-27 | — | — | EP | disclosed |
| EP-1182239-A2 | Ink Jet Ink composition | EASTMAN KODAK COMPANY (US) | 2002-02-27 | — | — | EP | disclosed |
| EP-1182238-A1 | Ink jet printing method | EASTMAN KODAK COMPANY (US) | 2002-02-27 | — | — | EP | disclosed |
| EP-1182050-A2 | Ink jet printing method | EASTMAN KODAK COMPANY (US) | 2002-02-27 | — | — | EP | disclosed |
| EP-0368410-A2 | Optically active benzoxazines and bezothiazines and a process for their stereospecific preparation | GIST-BROCADES N.V. (NL) | 1990-05-16 | — | — | EP | disclosed |
| US-4282358-A | CYCLIZATION OF 2-HALOPHENOXYANILINES | CIBA-GEIGY CORPORATION (US) | 1981-08-04 | — | — | US | disclosed |
| US-4282358-A | CYCLIZATION OF 2-HALOPHENOXYANILINES | CIBA-GEIGY CORPORATION (US) | 1981-08-04 | — | — | US | disclosed |
| US-4282358-A | CYCLIZATION OF 2-HALOPHENOXYANILINES | CIBA-GEIGY CORPORATION (US) | 1981-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140128408-A1 | HDAC INHIBITORS AND THERAPEUTIC METHODS USING THE SAME | HDAC1, HDAC9, HDAC8 | BRD4 184/4885CCL2 3704/4885MEN1 1417/4885 |
| US-20040209875-A1 | Nonsteroidal antiinflammatory agents | PTGS1, PTGER1, PTGES | BRD4 3166/4885CCL2 178/4885MEN1 1721/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.