SCHEMBL3342677

SCHEMBL3342677

CC(C)(C)OC(=O)N1CCC(c2ccc(COc3ccc(S(C)(=O)=O)cc3F)cc2)CC1

nearest known ligand 0.61

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 20/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3344962 0.85 GPR119 (0.41) GPR119
SCHEMBL3347296 0.83 GPR119 (0.55) GPR119
SCHEMBL1557797 0.82 GPR119 (0.57) GPR119
SCHEMBL1575800 0.81 GPR119 (0.80) GPR119
SCHEMBL1118187 0.81 GPR119 (0.66) GPR119
SCHEMBL4519083 0.81 GPR119 (0.76) GPR119
SCHEMBL4282041 0.80 GPR119 (0.59) GPR119
SCHEMBL1557884 0.80 GPR119 (0.70) GPR119
SCHEMBL3767218 0.79 GPR119 (0.58) GPR119
SCHEMBL3348799 0.78 SLC6A4 (0.50) GPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010048149-A2 HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE KALYPSYS, INC. (US) 2010-04-29 WO disclosed