Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 9/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.50 |
| ▸ | HTR1A | P08908 | 7/20 | 0.50 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 5/20 | 0.44 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.40 |
| ▸ | CDK9 | P50750 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3346815 | 0.99 | SLC6A4 (0.49) | SLC6A4SLC6A2SLC6A3HTR1APRMT5 | |
| SCHEMBL3344962 | 0.83 | GPR119 (0.41) | PTGER1SLC6A9GPR119 | |
| SCHEMBL3342677 | 0.78 | GPR119 (0.61) | GPR119 | |
| SCHEMBL3342692 | 0.78 | GPR119 (0.59) | GPR119 | |
| SCHEMBL1556570 | 0.78 | SLC6A4 (0.40) | SLC6A4SLC6A2SLC6A3HTR1APRMT5 | |
| SCHEMBL1118288 | 0.77 | GPR119 (0.46) | SLC6A4SLC6A2SLC6A3HTR1APRMT5 | |
| SCHEMBL17334213 | 0.76 | PLAT (0.46) | SLC6A9GPR119 | |
| SCHEMBL11305746 | 0.75 | HTR2C (0.53) | SLC6A4SLC6A2SLC6A3PRMT5HTR6 | |
| SCHEMBL4170969 | 0.75 | SLC18A3 (0.52) | HTR6 | |
| SCHEMBL7591442 | 0.74 | GPR119 (0.38) | SLC6A9GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010048149-A2 | HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2010-04-29 | — | — | WO | disclosed |