Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.41 |
| ▸ | SLC6A9 | P48067 | 3/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3342677 | 0.85 | GPR119 (0.61) | GPR119 | |
| SCHEMBL3348799 | 0.83 | SLC6A4 (0.50) | GPR119SLC6A9PTGER1 | |
| Hydrochloric Acid SCHEMBL3346815 | 0.82 | SLC6A4 (0.49) | GPR119SLC6A9PTGER1 | |
| SCHEMBL3342692 | 0.81 | GPR119 (0.59) | GPR119CYP3A4KCNH2 | |
| SCHEMBL22458967 | 0.77 | GPR119 (0.46) | GPR119DRD2SIGMAR1 | |
| SCHEMBL3343263 | 0.75 | LSS (0.37) | GPR119DRD2KCNH2 | |
| SCHEMBL1577770 | 0.72 | GPR119 (0.42) | GPR119SLC6A9KCNH2 | |
| SCHEMBL22458966 | 0.70 | DRD2 (0.64) | GPR119DRD2SIGMAR1 | |
| SCHEMBL16590855 | 0.69 | ESR2 (0.42) | S1PR5 | |
| SCHEMBL3347296 | 0.67 | GPR119 (0.55) | GPR119CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010048149-A2 | HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2010-04-29 | — | — | WO | disclosed |