SCHEMBL334270

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1008180	0.84	HTR7 (0.43)	PIK3CDPIK3CAPIK3CBPIK3CGHTR7
	SCHEMBL3905475	0.84	CYP4F2 (0.36)	PIK3CDPIK3CAPIK3CBPIK3CGXDH
	SCHEMBL27748078	0.81	PIK3CD (0.33)	PIK3CDPIK3CAPIK3CBPIK3CGXDH
	SCHEMBL10271333	0.81	PKM (0.42)	SLC22A12NPC1PKMKDM4ETDP1
	SCHEMBL2118714	0.81	XDH (0.35)	PIK3CDPIK3CAPIK3CBPIK3CGXDH
	SCHEMBL334082	0.79	SLC22A12 (0.40)	SLC22A12NPC1RAB9ATDP1PTPN1
	SCHEMBL3033490	0.79	TSHR (0.40)	PIK3CDPIK3CAPIK3CBPIK3CGKDM4E
	SCHEMBL6155856	0.77	SLC22A12 (0.38)	SLC22A12NPC1KDM4ETDP1PTPN1
	SCHEMBL1234544	0.76	SLC22A12 (0.62)	SLC22A12ENPP2KDM4ETDP1MMP3
	SCHEMBL14472635	0.76	AR (0.50)	XDHALDH1A1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.