Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.37 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.36 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.36 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 3/20 | 0.35 |
| ▸ | PARP1 | P09874 | 3/20 | 0.35 |
| ▸ | PLK4 | O00444 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.35 |
| ▸ | LTK | P29376 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1210909 | 0.84 | HCAR2 (0.42) | KDM4EL3MBTL1CSNK1A1DYRK1BTYRO3 | |
| Pyrrole SCHEMBL2297382 | 0.83 | BTK (0.39) | KDM4EL3MBTL1CSNK1A1DYRK1BTYRO3 | |
| SCHEMBL82637 | 0.71 | NAPRT (0.67) | KDM4ENAPRTCSNK1A1DYRK1BTYRO3 | |
| Hydrochloric Acid SCHEMBL30935942 | 0.70 | NAPRT (0.64) | KDM4ENAPRTCSNK1A1DYRK1BTYRO3 | |
| SCHEMBL2742976 | 0.68 | HCAR2 (0.54) | KDM4EL3MBTL1NAPRTALDH1A1MAPT | |
| Urea SCHEMBL11275543 | 0.68 | MAPT (0.47) | L3MBTL1PARP1ALDH1A1MAPTHPGD | |
| SCHEMBL2230617 | 0.68 | CES2 (0.47) | L3MBTL1NAPRTCDK5ALDH1A1RAB9A | |
| SCHEMBL2232981 | 0.67 | P2RX7 (0.46) | KDM4ECSNK1A1DYRK1BTYRO3PARP1 | |
| SCHEMBL27189220 | 0.67 | HCAR2 (0.42) | L3MBTL1PARP1ALDH1A1HSD17B10PIM1 | |
| SCHEMBL243709 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010024911-A1 | METHODS FOR INCREASING NEUROGENESIS | FIBROGEN, INC. (US) | 2010-03-04 | — | — | WO | disclosed |