Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.62 |
| ▸ | RELA | Q04206 | 1/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | TNKS | O95271 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3343041 | 1.00 | CTDSP1 (0.62) | CTDSP1RELAGLATDP1MAPT | |
| SCHEMBL440963 | 0.82 | KDM4E (0.48) | GLAMAPTSMN1; SMN2NPC1RAB9A | |
| Water SCHEMBL28741447 | 0.80 | KDM4E (0.47) | GLAMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL3345880 | 0.79 | SMN1; SMN2 (0.52) | MAPTSMN1; SMN2KMT2AHDAC1ALDH1A1 | |
| (Z)-1,2-Diphenylethene SCHEMBL7706163 | 0.77 | GLA (0.70) | GLATDP1MAPTSMN1; SMN2CYP1B1 | |
| (Z)-1,2-Diphenylethene SCHEMBL7706161 | 0.77 | GLA (0.70) | GLATDP1MAPTSMN1; SMN2CYP1B1 | |
| Acetohydroxamic Acid SCHEMBL28769569 | 0.77 | MTNR1A (0.44) | CTDSP1GLAMAPTSMN1; SMN2NPC1 | |
| (Z)-1,2-Diphenylethene SCHEMBL8417390 | 0.75 | GLA (0.67) | GLATDP1MAPTSMN1; SMN2CYP1B1 | |
| (Z)-1,2-Diphenylethene SCHEMBL8903561 | 0.75 | GLA (0.67) | GLATDP1MAPTSMN1; SMN2CYP1B1 | |
| (Z)-1,2-Diphenylethene SCHEMBL5960443 | 0.73 | GLA (0.64) | GLATDP1MAPTSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100162416-A1 | Multi-stage stem cell carcinogenesis | STEMLIFELINE, INC. (US) | 2010-06-24 | — | — | US | disclosed |
| WO-2010037134-A2 | MULTI-STAGE STEM CELL CARCINOGENESIS | STEMLIFELINE, INC. (US) | 2010-04-01 | — | — | WO | disclosed |