Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | FASN | P49327 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL440963 | 0.87 | KDM4E (0.48) | SMN1; SMN2MAPTALDH1A1KDM4EHPGD | |
| Water SCHEMBL28741447 | 0.85 | KDM4E (0.47) | SMN1; SMN2MAPTALDH1A1KDM4EHPGD | |
| SCHEMBL3297266 | 0.81 | MAPT (0.54) | SMN1; SMN2MAPTALDH1A1KDM4EHPGD | |
| SCHEMBL4870751 | 0.81 | MAPT (0.54) | SMN1; SMN2MAPTALDH1A1KDM4EHPGD | |
| SCHEMBL1177869 | 0.79 | ALDH1A1 (0.53) | SMN1; SMN2MAPTALDH1A1KDM4EUSP2 | |
| SCHEMBL3343044 | 0.79 | CTDSP1 (0.62) | SMN1; SMN2MAPTALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL3343041 | 0.79 | CTDSP1 (0.62) | SMN1; SMN2MAPTALDH1A1KMT2AL3MBTL1 | |
| Acetohydroxamic Acid SCHEMBL28769569 | 0.78 | MTNR1A (0.44) | SMN1; SMN2MAPTALDH1A1KDM4EHPGD | |
| SCHEMBL1948081 | 0.76 | MAPT (0.48) | SMN1; SMN2MAPTALDH1A1KDM4EHPGD | |
| SCHEMBL27534541 | 0.76 | KMT2A (0.47) | MAPTALDH1A1KDM4EHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100162416-A1 | Multi-stage stem cell carcinogenesis | STEMLIFELINE, INC. (US) | 2010-06-24 | — | — | US | disclosed |
| WO-2010037134-A2 | MULTI-STAGE STEM CELL CARCINOGENESIS | STEMLIFELINE, INC. (US) | 2010-04-01 | — | — | WO | disclosed |
| EP-1137769-B1 | METHODS FOR THE GENERATION OF DNA LIBRARIES | UNIV ROCHESTER (US) | 2008-09-03 | — | — | EP | disclosed |
| US-20060160129-A1 | Methods of producing a library and methods of selecting polynucleotides of interest | UNIVERSITY OF ROCHESTER (US) | 2006-07-20 | — | — | US | disclosed |
| US-7067251-B2 | Methods of directly selecting cells expressing inserts of interest | UNIVERSITY OF ROCHESTER (US) | 2006-06-27 | — | — | US | disclosed |
| US-6872518-B2 | Methods for selecting polynucleotides encoding T cell epitopes | UNIVERSITY OF ROCHESTER (US) | 2005-03-29 | — | — | US | disclosed |
| US-6800442-B2 | Methods of selecting polynucleotides encoding antigens | UNIVERSITY OF ROCHESTER | 2004-10-05 | — | — | US | disclosed |
| US-6706477-B2 | CELL DIFFERENTIATION; ANTITUMOR, ANTICANCER AGENTS | UNIVERSITY OF ROCHESTER | 2004-03-16 | — | — | US | disclosed |
| EP-1137769-A1 | T CELLS SPECIFIC FOR TARGET ANTIGENS AND METHODS AND VACCINES BASED THEREON | UNIVERSITY OF ROCHESTER (US) | 2001-10-04 | — | — | EP | disclosed |
| WO-2000028016-A1 | T CELLS SPECIFIC FOR TARGET ANTIGENS AND METHODS AND VACCINES BASED THEREON | UNIVERSITY OF ROCHESTER (US) | 2000-05-18 | — | — | WO | disclosed |